Proton-coupled amino acid transporter 2 (Proton/amino acid transporter 2) (Solute carrier family 36 member 2) (Transmembrane domain rich protein 1) (Tramdorin-1)
1_MSVTK 6_ STEGP 11_ QGAVA 16_ IKLDL 21_ MSPPE 26_ SAKKL 31_ ENKDS 36_ TFLDE 41_ SPSES 46_ AGLKK 51_ TKGIT 56_ VFQAL 61_ IHLVK 66_ GNMGT 71_ GILGL 76_ PLAVK 81_ NAGIL 86_ MGPLS 91_ LLVMG 96_ FIACH 101_ CMHIL 106_ VKCAQ 111_ RFCKR 116_ LNKPF 121_ MDYGD 126_ TVMHG 131_ LEANP 136_ NAWLQ 141_ NHAHW 146_ GRHIV 151_ SFFLI 156_ ITQLG 161_ FCCVY 166_ IVFLA 171_ DNLKQ 176_ VVEAV 181_ NSTTN 186_ NCYSN 191_ ETVIL 196_ TPTMD 201_ SRLYM 206_ LSFLP 211_ FLVLL 216_ VLIRN 221_ LRILT 226_ IFSML 231_ ANISM 236_ LVSLV 241_ IIIQY 246_ ITQEI 251_ PDPSR 256_ LPLVA 261_ SWKTY 266_ PLFFG 271_ TAIFS 276_ FESIG 281_ VVLPL 286_ ENKMK 291_ NARHF 296_ PAILS 301_ LGMSI 306_ VTSLY 311_ IGMAA 316_ LGYLR 321_ FGDDI 326_ KASIS 331_ LNLPN 336_ CWLYQ 341_ SVKLL 346_ YIAGI 351_ LCTYA 356_ LQFYV 361_ PAEII 366_ IPFAI 371_ SRVST 376_ RWALP 381_ LDLSI 386_ RLVMV 391_ CLTCL 396_ LAILI 401_ PRLDL 406_ VISLV 411_ GSVSG 416_ TALAL 421_ IIPPL 426_ LEVTT 431_ FYSEG 436_ MSPLT 441_ IFKDA 446_ LISIL 451_ GFVGF 456_ VVGTY 461_ QALDE 466_ LLKSE 471_ DSHPF 476_SNSTT
1: Electrogenic proton/amino acid symporter with a high selectivity for the small side chains amino acids glycine, alanine and proline, where both L- and D-enantiomers are transported. Extension of the backbone length, as in beta-alanine and 4-aminobutanoate or methylation of the amino group, as in sarcosine and N,N-dimethylglycine, are also tolerated but decrease transport efficiency. A free carboxyl group is preferred