C2 domain-containing protein 3
1_MKQRK 6_ GQGSG 11_ GSRGR 16_ KKRGL 21_ SDISP 26_ STSLP 31_ PLVEG 36_ QLRCF 41_ LKLTV 46_ NRVIW 51_ KIAKP 56_ PTCVL 61_ VRVRW 66_ WGETS 71_ DGTLF 76_ CPRDA 81_ LQTEP 86_ KAVRT 91_ TTRYA 96_ IRCGP 101_ KQFTS 106_ YLTDM 111_ AVLVL 116_ EVITK 121_ LDGLP 126_ IGRVQ 131_ INGLA 136_ QLSPT 141_ HQING 146_ FFTIV 151_ SSTSK 156_ KLGEL 161_ QVSLA 166_ LEPLS 171_ ETYDS 176_ YHPLP 181_ TTDMT 186_ ENVLL 191_ SKQGF 196_ RENTE 201_ PSSTQ 206_ FQVPS 211_ RPRDI 216_ HTIKI 221_ DGKEL 226_ AANSS 231_ RSTTP 236_ RGKDH 241_ VCFAE 246_ NPDTI 251_ KDSSF 256_ GLQHS 261_ LNSGQ 266_ SLESV 271_ TLKGR 276_ APRKQ 281_ MSLLN 286_ SSEFQ 291_ PQIRT 296_ VAKSH 301_ SDSCI 306_ LSSNN 311_ LPTKD 316_ LLSAL 321_ LEQGN 326_ KLRNA 331_ MVISA 336_ MKSSP 341_ ETSML 346_ LDQVH 351_ PPINE 356_ DSLRA 361_ STQIR 366_ AFSRN 371_ RFKDH 376_ IEDHL 381_ LPSTE 386_ NTFWR 391_ HDTKA 396_ DTRAI 401_ QLLLG 406_ SAELS 411_ QGNFW 416_ DGLGS 421_ PPDSP 426_ SPGSD 431_ VYCIS 436_ ELNDP 441_ QYDQS 446_ LLENL 451_ FYTAP 456_ KSDTS 461_ ISDFL 466_ SEEDD 471_ IVPSK 476_ KISQS 481_ TALAR 486_ SSKVL 491_ ESSDH 496_ KLKKR 501_ SAGKR 506_ NRNLV 511_ EQQML 516_ SETPE 521_ DAQTM 526_ TLSVD 531_ RLALL 536_ GRTHS 541_ VRIII 546_ ETMGV 551_ PPDSP 556_ QMTPG 561_ KKSYA 566_ GPPPK 571_ VTTAK 576_ KRTFF 581_ VEYHF 586_ PVGFS 591_ ESGLG 596_ KTALI 601_ TEVVR 606_ LASSK 611_ ITDGK 616_ VKFQQ 621_ RFVFP 626_ VQFGG 631_ PMIEH 636_ WWNSN 641_ LTFQI 646_ YVKKT 651_ PQKKP 656_ EVIGS 661_ VSLSL 666_ RAVIQ 671_ SELLS 676_ FSDQL 681_ PVQQE 686_ NGQSP 691_ FGPLK 696_ VTMEL 701_ ITDNK 706_ DFTGI 711_ NTKLS 716_ GNTHY 721_ TPLCA 726_ PTSPN 731_ KALPE 736_ LNQDM 741_ TCTKN 746_ PQNLN 751_ QIHEE 756_ TAKKA 761_ QNLVL 766_ PNRKS 771_ PSPVA 776_ PHPST 781_ FVATP 786_ ASHNL 791_ VNQTN 796_ GTTKE 801_ SALLL 806_ HVLLM 811_ VPDGK 816_ DFISG 821_ ESEKQ 826_ SPCNV 831_ YLNCK 836_ LFSTE 841_ EVTRS 846_ VIAWG 851_ TTQPV 856_ FNFSQ 861_ VIPVS 866_ LSSKY 871_ LERLK 876_ NNVMV 881_ IETWN 886_ KVRSP 891_ GQDKL 896_ LGLVK 901_ LPLHQ 906_ FYMSF 911_ KDAKI 916_ SRLLL 921_ DAQYP 926_ VVAVD 931_ SYMPV 936_ IDVFS 941_ GHQNG 946_ SLRVF 951_ LAMGS 956_ SNQIM 961_ ALQRL 966_ KNEEG 971_ TLPPF 976_ SPRPA 981_ HFLDQ 986_ PTAAS 991_ VAMAE 996_ DRGNG 1001_ LMEHC 1006_ FEIHI 1011_ EMVKG 1016_ LAPLQ 1021_ ATVWG 1026_ EADCY 1031_ VQYYF 1036_ PVQHS 1041_ QSSVL 1046_ KGPEF 1051_ LENGI 1056_ TLKPF 1061_ RTATT 1066_ LCVPD 1071_ PIFNS 1076_ EHHHS 1081_ LLLPA 1086_ EVPVQ 1091_ RLLLS 1096_ AFSAQ 1101_ GLVPG 1106_ GGVQF 1111_ EIWCR 1116_ YYYPN 1121_ VRDQK 1126_ VAKGT 1131_ LPLSR 1136_ ICAMV 1141_ TTQHR 1146_ EDVGI 1151_ QTFNL 1156_ PLTPR 1161_ IENRK 1166_ ELRNQ 1171_ SSGLL 1176_ DVGLR 1181_ YRRSP 1186_ RTAEG 1191_ VLAAR 1196_ TVSIS 1201_ VQIIR 1206_ ACGLQ 1211_ AAAKA 1216_ LAERE 1221_ PALQF 1226_ SATVG 1231_ VNASV 1236_ TTHLS 1241_ FLPQG 1246_ EQRRT 1251_ HPVAC 1256_ SFCPE 1261_ FSHHV 1266_ EFTCN 1271_ LVTQH 1276_ CSGEA 1281_ CFLAE 1286_ LLEFA 1291_ EVIFA 1296_ VYHEN 1301_ TKSAS 1306_ DIISI 1311_ ESCKE 1316_ YLLGV 1321_ VKVPT 1326_ KELLI 1331_ KRSGI 1336_ TGWYP 1341_ IILPE 1346_ DGGLP 1351_ HGLEL 1356_ MQKIV 1361_ GGLEL 1366_ SISFT 1371_ HRGDR 1376_ ERVLE 1381_ AAEHL 1386_ GWSFE 1391_ NSLKD 1396_ FVRMD 1401_ EGEPA 1406_ TVTIS 1411_ TPRLW 1416_ LPIHC 1421_ VLLAG 1426_ HNHIH 1431_ KNTYC 1436_ YLRYK 1441_ FYDHE 1446_ AFWTP 1451_ LKKPK 1456_ ESVNK 1461_ KQIMV 1466_ TFKAS 1471_ KRAEV 1476_ TRGPS 1481_ LLWYF 1486_ REERL 1491_ EIQVW 1496_ RAYGN 1501_ DSVER 1506_ PHQTD 1511_ SWIGS 1516_ AYVDL 1521_ ARLGE 1526_ RSART 1531_ LTVSG 1536_ VYPLF 1541_ GRNAS 1546_ NLSGA 1551_ ALRVH 1556_ VVLSS 1561_ LSSHL 1566_ EPTHE 1571_ LDSMD 1576_ CSSHS 1581_ ESEQL 1586_ PRRND 1591_ EVQLS 1596_ PPEVI 1601_ SCHQK 1606_ SPAST 1611_ QVPCS 1616_ STTAE 1621_ VRLTQ 1626_ EGPAD 1631_ LDGTF 1636_ AVSIL 1641_ VERAM 1646_ HLSLK 1651_ GSPLT 1656_ ERKVS 1661_ IPSCC 1666_ VSFAT 1671_ ADESS 1676_ PVYTQ 1681_ VVENT 1686_ DSPIW 1691_ NFQQQ 1696_ SRLSK 1701_ ELLLD 1706_ PQQTL 1711_ VFKVW 1716_ HKGDE 1721_ ERVIG 1726_ FASVD 1731_ LSPLL 1736_ SGFQF 1741_ VCGWY 1746_ NITDF 1751_ SGECQ 1756_ GQIKV 1761_ AVSPL 1766_ ESLIH 1771_ FKEER 1776_ QARRG 1781_ VETSK 1786_ SLIPI 1791_ YSPFS 1796_ FPASD 1801_ TYAAF 1806_ SSHMA 1811_ RQTLD 1816_ QLAHA 1821_ SSKEL 1826_ DFSSP 1831_ GRSDT 1836_ TRSQA 1841_ SRHEE 1846_ HVQNI 1851_ RRFHE 1856_ SLHLQ 1861_ GEAPL 1866_ PCDDK 1871_ LTTSP 1876_ LSSQT 1881_ SILTS 1886_ LRKNL 1891_ SELDQ 1896_ IQRYF 1901_ RQKLT 1906_ KPFLP 1911_ LSPQT 1916_ QTAIS 1921_ QHQES 1926_ CRDHL 1931_ GPGAS 1936_ SLDPG 1941_ SQCIL 1946_ EKSSN 1951_ LVLQV 1956_ SSLIT 1961_ DLQTI 1966_ TRDSQ 1971_ AALSS 1976_ HRARS 1981_ RSNKA 1986_ TTLPD 1991_ AQDTE 1996_ ALQER 2001_ CTMPD 2006_ EPLVR 2011_ APDKG 2016_ TDSPS 2021_ PPPLE 2026_ ETSNG 2031_ GRMLH 2036_ ESLRH 2041_ AVPIT 2046_ RMQSS 2051_ EDTEA 2056_ GPAYS 2061_ DEDYE 2066_ EDIIE 2071_ PRTLN 2076_ EITTV 2081_ TDKTS 2086_ PWSSV 2091_ ISDTS 2096_ EVISP 2101_ QPDEV 2106_ QREGP 2111_ SCPSP 2116_ GPFCR 2121_ EELMV 2126_ KSSFL 2131_ SSPER 2136_ AVNPH 2141_ LPRQG 2146_ SPSQS 2151_ LVACE 2156_ CEASK 2161_ ARVGG 2166_ ESASA 2171_ NPQPI 2176_ PCPTL 2181_ SGAQQ 2186_ SSTFV 2191_ GWSSP 2196_ QTDQN 2201_ KEPKS 2206_ EAPAE 2211_ NEAAT 2216_ SELGD 2221_ SADSF 2226_ KKLPL 2231_ NLASQ 2236_ SRREN 2241_ HKGPP 2246_ IDSSD 2251_ IRQRQ 2256_ VTTGS 2261_ ETSTK 2266_ QSLLL 2271_ PGPIV 2276_ VPNFF 2281_ LPPQQ 2286_ LEASL 2291_ RMLSL 2296_ SATLP 2301_ PAATT 2306_ DQDKS 2311_ EATRG 2316_ ALSQR 2321_ PCRPR 2326_ PNSLP 2331_ LNLPE 2336_ EETLR 2341_ IARIF 2346_SSQYS
1: Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3