F-box only protein 43 (Endogenous meiotic inhibitor 2)
1_MSFKD 6_ KDERI 11_ SCLEA 16_ YVTLT 21_ SKSSR 26_ FTDET 31_ EILKM 36_ SQRHS 41_ GQAGT 46_ EAGNG 51_ ADSPP 56_ IVNSK 61_ YSTFR 66_ DFCST 71_ SSFQD 76_ SGYNE 81_ LKSCS 86_ FDNID 91_ KEYLG 96_ KKEKG 101_ PTLLY 106_ EHPET 111_ SGLGL 116_ THPLE 121_ SPTQK 126_ KKCIL 131_ PRKEK 136_ DKTPE 141_ LCETP 146_ KISGK 151_ KCLPR 156_ RRLNV 161_ SFALL 166_ KGDFE 171_ SQNSS 176_ LESSI 181_ SQVIN 186_ LEKNI 191_ PSSAS 196_ GFSRA 201_ NNFSP 206_ LVTST 211_ LKTEE 216_ VTSCS 221_ QKLRL 226_ NFSQQ 231_ KTSTI 236_ DDSKD 241_ DCSLF 246_ EVECI 251_ SPIQG 256_ NNFKD 261_ SITHD 266_ FSDSS 271_ LCIND 276_ ENACP 281_ ELLGS 286_ SVSGT 291_ TCGTD 296_ EDIFV 301_ TPISN 306_ LVANI 311_ RFNAS 316_ QILSP 321_ SPEVR 326_ GSIST 331_ PEDSG 336_ FNSLS 341_ LEKSE 346_ DSLSD 351_ QEGSF 356_ QELLQ 361_ KHKGT 366_ PKVGD 371_ TIRKT 376_ RHLGR 381_ SRRLS 386_ TLREQ 391_ SSQSE 396_ TEEEK 401_ QIVHP 406_ DSEKR 411_ AAAAS 416_ AISEG 421_ QLSSD 426_ ESGDL 431_ TFSLK 436_ NLSKT 441_ PALQL 446_ VHELF 451_ MKSKR 456_ KRLQE 461_ NSGHE 466_ FLEQG 471_ DGEKI 476_ AVLQC 481_ ILAGL 486_ IGKKM 491_ GIEKL 496_ DILTE 501_ LKYRN 506_ LKHIL 511_ AMVLE 516_ SLTAE 521_ SLCSV 526_ WKVSR 531_ NWREI 536_ VVQDK 541_ NANRR 546_ RKFYI 551_ TQLKT 556_ DSEGA 561_ VLNVE 566_ DAATR 571_ LQLLN 576_ RSALR 581_ SVQAQ 586_ ARIPG 591_ SQREQ 596_ GSTLS 601_ PWGEV 606_ LTPLA 611_ SSSVT 616_ HLSSK 621_ QEEYV 626_ KVAKT 631_ LFTDE 636_ ALKPC 641_ PRCQS 646_ PAKYQ 651_ PYKKR 656_ GLCSR 661_ TACGF 666_ DFCVL 671_ CLCAY 676_ HGSEE 681_ CSRGA 686_ AKPRN 691_ RKDAL 696_ PGSAQ 701_SKRNL
1: Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (PubMed:34052850, PubMed:34595750). Plays a vital role in modulating the ubiquitilation of CCNB1 and CDK1 during gametogenesis