1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3)
1_MADLE 6_ VYKNL 11_ SPEKV 16_ ERCMS 21_ VMQSG 26_ TQMIK 31_ LKRGT 36_ KGLVR 41_ LFYLD 46_ EHRTR 51_ LRWRP 56_ SRKSE 61_ KAKIL 66_ IDSIY 71_ KVTEG 76_ RQSEI 81_ FHRQA 86_ EGNFD 91_ PSCCF 96_ TIYHG 101_ NHMES 106_ LDLIT 111_ SNPEE 116_ ARTWI 121_ TGLKY 126_ LMAGI 131_ SDEDS 136_ LAKRQ 141_ RTHDQ 146_ WVKQT 151_ FEEAD 156_ KNGDG 161_ LLNIE 166_ EIHQL 171_ MHKLN 176_ VNLPR 181_ RKVRQ 186_ MFQEA 191_ DTDEN 196_ QGTLT 201_ FEEFC 206_ VFYKM 211_ MSLRR 216_ DLYLL 221_ LLSYS 226_ DKKDH 231_ LTVEE 236_ LAQFL 241_ KVEQK 246_ MNNVT 251_ TDYCL 256_ DIIKK 261_ FEVSE 266_ ENKVK 271_ NVLGI 276_ EGFTN 281_ FMRSP 286_ ACDIF 291_ NPLHH 296_ EVYQD 301_ MDQPL 306_ CNYYI 311_ ASSHN 316_ TYLTG 321_ DQLLS 326_ QSKVD 331_ MYARV 336_ LQEGC 341_ RCVEV 346_ DCWDG 351_ PDGEP 356_ VVHHG 361_ YTLTS 366_ KILFR 371_ DVVET 376_ INKHA 381_ FVKNE 386_ FPVIL 391_ SIENH 396_ CSIQQ 401_ QRKIA 406_ QYLKG 411_ IFGDK 416_ LDLSS 421_ VDTGE 426_ CKQLP 431_ SPQSL 436_ KGKIL 441_ VKGKK 446_ LPYHL 451_ GDDAE 456_ EGEVS 461_ DEDSA 466_ DEIED 471_ ECKFK 476_ LHYSN 481_ GTTEH 486_ QVESF 491_ IRKKL 496_ ESLLK 501_ ESQIR 506_ DKEDP 511_ DSFTV 516_ RALLK 521_ ATHEG 526_ LNAHL 531_ KQSPD 536_ VKESG 541_ KKSHG 546_ RSLMT 551_ NFGKH 556_ KKTTK 561_ SRSKS 566_ YSTDD 571_ EEDTQ 576_ QSTGK 581_ EGGQL 586_ YRLGR 591_ RRKTM 596_ KLCRE 601_ LSDLV 606_ VYTNS 611_ VAAQD 616_ IVDDG 621_ TTGNV 626_ LSFSE 631_ TRAHQ 636_ VVQQK 641_ SEQFM 646_ IYNQK 651_ QLTRI 656_ YPSAY 661_ RIDSS 666_ NFNPL 671_ PYWNA 676_ GCQLV 681_ ALNYQ 686_ SEGRM 691_ MQLNR 696_ AKFKA 701_ NGNCG 706_ YVLKP 711_ QQMCK 716_ GTFNP 721_ FSGDP 726_ LPANP 731_ KKQLI 736_ LKVIS 741_ GQQLP 746_ KPPDS 751_ MFGDR 756_ GEIID 761_ PFVEV 766_ EIIGL 771_ PVDCC 776_ KDQTR 781_ VVDDN 786_ GFNPV 791_ WEETL 796_ TFTVH 801_ MPEIA 806_ LVRFL 811_ VWDHD 816_ PIGRD 821_ FVGQR 826_ TVTFS 831_ SLVPG 836_ YRHVY 841_ LEGLT 846_ EASIF 851_ VHITI 856_ NEIYG 861_ KWSPL 866_ ILNPS 871_ YTILH 876_ FLGAT 881_ KNRQL 886_ QGLKG 891_ LFNKN 896_ PRHSS 901_ SENNS 906_ HYVRK 911_ RSIGD 916_ RILRR 921_ TASAP 926_ AKGRK 931_ KSKMG 936_ FQEMV 941_ EIKDS 946_ VSEAT 951_ RDQDG 956_ VLRRT 961_ TRSLQ 966_ ARPVS 971_ MPVDR 976_ NLLGA 981_ LSLPV 986_ SETAK 991_ DIEGK 996_ ENSLA 1001_ EDKDG 1006_ RRKGK 1011_ ASIKD 1016_ PHFLN 1021_ FNKKL 1026_ SSSSS 1031_ ALLHK 1036_ DTSQG 1041_ DTIVS 1046_ TAHMS 1051_ VTGEQ 1056_ LGMSS 1061_ PRGGR 1066_ TTSNA 1071_ TSNCQ 1076_ ENPCP 1081_ SKSLS 1086_ PKQHL 1091_ APDPV 1096_ VNPTQ 1101_ DLHGV 1106_ KIKEK 1111_ GNPED 1116_ FVEGK 1121_ SILSG 1126_ SVLSH 1131_ SNLEI 1136_ KNLEG 1141_ NRGKG 1146_ RAATS 1151_ FSLSD 1156_ VSMLC 1161_ SDIPD 1166_ LHSTA 1171_ ILQES 1176_ VISHL 1181_ IDNVT 1186_ LTNEN 1191_ EPGSS 1196_ ISALI 1201_ GQFDE 1206_ TNNQA 1211_ LTVVS 1216_ HLHNT 1221_ SVMSG 1226_ HCPLP 1231_ SLGLK 1236_ MPIKH 1241_ GFCKG 1246_ KSKSS 1251_ FLCSS 1256_ PELIA 1261_ LSSSE 1266_ TTKHA 1271_ TNTVY 1276_ ETTCT 1281_ PISKT 1286_ KPDDD 1291_ LSSKA 1296_ KTAAL 1301_ ESNLP 1306_ GSPNT 1311_ SRGWL 1316_ PKSPT 1321_ KGEDW 1326_ ETLKS 1331_ CSPAS 1336_ SPDLT 1341_ LEDVI 1346_ ADPTL 1351_ CFNSG 1356_ ESSLV 1361_ EIDGE 1366_ SENLS 1371_ LTTCE 1376_ YRREG 1381_ TSQLA 1386_ SPLKL 1391_ KYNQG 1396_ VVEHF 1401_ QRGLR 1406_ NGYCK 1411_ ETLRP 1416_ SVPEI 1421_ FNNIQ 1426_ DVKTQ 1431_ SISYL 1436_ AYQGA 1441_ GFVHN 1446_ HFSDS 1451_ DAKMF 1456_ QTCVP 1461_ QQSSA 1466_ QDMHV 1471_ PVPKQ 1476_ LAHLP 1481_ LPALK 1486_ LPSPC 1491_ KSKSL 1496_ GDLTS 1501_ EDIAC 1506_ NFESK 1511_ YQCIS 1516_ KSFVT 1521_ TGIRD 1526_ KKGVT 1531_ VKTKS 1536_ LEPID 1541_ ALTEQ 1546_ LRKLV 1551_ SFDQE 1556_ DNCQV 1561_ LYSKQ 1566_ DANQL 1571_ PRALV 1576_ RKLSS 1581_ RSQSR 1586_ VRNIA 1591_ SRAKE 1596_ KQEAN 1601_ KQKVP 1606_ NPSNG 1611_ AGVVL 1616_ RNKPS 1621_ APTPA 1626_ VNRHS 1631_ TGSYI 1636_ AGYLK 1641_ NTKGG 1646_ GLEGR 1651_ GIPEG 1656_ ACTAL 1661_ HYGHV 1666_ DQFCS 1671_ DNSVL 1676_ QTEPS 1681_ SDDKP 1686_EIYFL
1: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes