Dynein axonemal light chain 1 (LC1)
1_MAKAT 6_ TIKEA 11_ LARWE 16_ EKTGQ 21_ RPSEA 26_ KEIKL 31_ YAQIP 36_ PIEKM 41_ DASLS 46_ MLANC 51_ EKLSL 56_ STNCI 61_ EKIAN 66_ LNGLK 71_ NLRIL 76_ SLGRN 81_ NIKNL 86_ NGLEA 91_ VGDTL 96_ EELWI 101_ SYNFI 106_ EKLKG 111_ IHIMK 116_ KLKIL 121_ YMSNN 126_ LVKDW 131_ AEFVK 136_ LAELP 141_ CLEDL 146_ VFVGN 151_ PLEEK 156_ HSAEN 161_ NWIEE 166_ ATKRV 171_ PKLKK 176_ LDGTP 181_VIKGD
1: Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787)