Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29)
1_MIAHK 6_ QKKTK 11_ KKRAW 16_ ASGQL 21_ STDIT 26_ TSEMG 31_ LKSLS 36_ SNSIF 41_ DPDYI 46_ KELVN 51_ DIRKF 56_ SHMLL 61_ YLKEA 66_ IFSDC 71_ FKEVI 76_ HIRLE 81_ ELLRV 86_ LKSIM 91_ NKHQN 96_ LNSVD 101_ LQNAA 106_ EMLTA 111_ KVKAV 116_ NFTEV 121_ NEENK 126_ NDLFQ 131_ EVFSS 136_ IETLA 141_ FTFGN 146_ ILTNF 151_ LMGDV 156_ GNDSL 161_ LRLPV 166_ SRETK 171_ SFENV 176_ SVESV 181_ DSSSE 186_ KGNFS 191_ PLELD 196_ NVLLK 201_ NTDSI 206_ ELALS 211_ YAKTW 216_ SKYTK 221_ NIVSW 226_ VEKKL 231_ NLELE 236_ STRNM 241_ VKLAE 246_ ATRTN 251_ IGIQE 256_ FMPLQ 261_ SLFTN 266_ ALLND 271_ IESSH 276_ LLQQT 281_ IAALQ 286_ ANKFV 291_ QPLLG 296_ RKNEM 301_ EKQRK 306_ EIKEL 311_ WKQEQ 316_ NKMLE 321_ AENAL 326_ KKAKL 331_ LCMQR 336_ QDEYE 341_ KAKSS 346_ MFRAE 351_ EEHLS 356_ SSGGL 361_ AKNLN 366_ KQLEK 371_ KRRLE 376_ EEALQ 381_ KVEEA 386_ NELYK 391_ VCVTN 396_ VEERR 401_ NDLEN 406_ TKREI 411_ LAQLR 416_ TLVFQ 421_ CDLTL 426_ KAVTV 431_ NLFHM 436_ QHLQA 441_ ASLAD 446_ SLQSL 451_ CDSAK 456_ LYDPG 461_ QEYSE 466_ FVKAT 471_ NSTEE 476_ EKVDG 481_ NVNKH 486_ LNSSQ 491_ PSGFG 496_ PANSL 501_ EDVVR 506_ LPDSS 511_ NKIEE 516_ DRCSN 521_ SADIT 526_ GPSFI 531_ RSWTF 536_ GMFSD 541_ SESTG 546_ GSSES 551_ RSLDS 556_ ESISP 561_ GDFHR 566_ KLPRT 571_ PSSGT 576_ MSSAD 581_ DLDER 586_ EPPSP 591_ SETGP 596_ NSLGT 601_ FKKTL 606_ MSKAA 611_ LTHKF 616_ RKLRS 621_ PTKCR 626_ DCEGI 631_ VVFQG 636_ VECEE 641_ CLLVC 646_ HRKCL 651_ ENLVI 656_ ICGHQ 661_ KLPGK 666_ IHLFG 671_ AEFTQ 676_ VAKKE 681_ PDGIP 686_ FILKI 691_ CASEI 696_ ENRAL 701_ CLQGI 706_ YRVCG 711_ NKIKT 716_ EKLCQ 721_ ALENG 726_ MHLVD 731_ ISEFS 736_ SHDIC 741_ DVLKL 746_ YLRQL 751_ PEPFI 756_ LFRLY 761_ KEFID 766_ LAKEI 771_ QHVNE 776_ EQETK 781_ KNSLE 786_ DKKWP 791_ NMCIE 796_ INRIL 801_ LKSKD 806_ LLRQL 811_ PASNF 816_ NSLHF 821_ LIVHL 826_ KRVVD 831_ HAEEN 836_ KMNSK 841_ NLGVI 846_ FGPSL 851_ IRPRP 856_ TTAPI 861_ TISSL 866_ AEYSN 871_ QARLV 876_ EFLIT 881_ YSQKI 886_ FDGSL 891_ QPQDV 896_ MCSIG 901_ VVDQG 906_ CFPKP 911_ LLSPE 916_ ERDIE 921_ RSMKS 926_ LFFSS 931_ KEDIH 936_ TSESE 941_ SKIFE 946_ RATSF 951_ EESER 956_ KQNAL 961_ GKCDA 966_ CLSDK 971_ AQLLL 976_ DQEAE 981_ SASQK 986_ IEDGK 991_ TPKPL 996_ SLKSD 1001_ RSTNN 1006_ VERHT 1011_ PRTKI 1016_ RPVSL 1021_ PVDRL 1026_ LLASP 1031_ PNERN 1036_ GRNMG 1041_ NVNLD 1046_ KFCKN 1051_ PAFEG 1056_ VNRKD 1061_ AATTV 1066_ CSKFN 1071_ GFDQQ 1076_ TLQKI 1081_ QDKQY 1086_ EQNSL 1091_ TAKTT 1096_ MIMPS 1101_ ALQEK 1106_ GVTTS 1111_ LQISG 1116_ DHSIN 1121_ ATQPS 1126_ KPYAE 1131_ PVRSV 1136_ REASE 1141_ RRSSD 1146_ SYPLA 1151_ PVRAP 1156_ RTLQP 1161_ QHWTT 1166_ FYKPH 1171_ APIIS 1176_ IRGNE 1181_ EKPAS 1186_ PSAAV 1191_ PPGTD 1196_ HDPHG 1201_ LVVKS 1206_ MPDPD 1211_ KASAC 1216_ PGQAT 1221_ GQPKE 1226_ DSEEL 1231_ GLPDV 1236_ NPMCQ 1241_ RPRLK 1246_ RMQQF 1251_ EDLEG 1256_EIPQF
1: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis