CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)
1_MATSG 6_ ANGPG 11_ SATAS 16_ ASNPR 21_ KFSEK 26_ IALQK 31_ QRQAE 36_ ETAAF 41_ EEVMM 46_ DIGST 51_ RLQAQ 56_ KLRLA 61_ YTRSS 66_ HYGGS 71_ LPNVN 76_ QIGSG 81_ LAEFQ 86_ SPLHS 91_ PLDSS 96_ RSTRH 101_ HGLVE 106_ RVQRD 111_ PRRMV 116_ SPLRR 121_ YTRHI 126_ DSSPY 131_ SPAYL 136_ SPPPE 141_ SSWRR 146_ TMAWG 151_ NFPAE 156_ KGQLF 161_ RLPSA 166_ LNRTS 171_ SDSAL 176_ HTSVM 181_ NPSPQ 186_ DTYPG 191_ PTPPS 196_ ILPSR 201_ RGGIL 206_ DGEMD 211_ PKVPA 216_ IEENL 221_ LDDKH 226_ LLKPW 231_ DAKKL 236_ SSSSS 241_ RPRSC 246_ EVPGI 251_ NIFPS 256_ PDQPA 261_ NVPVL 266_ PPAMN 271_ TGGSL 276_ PDLTN 281_ LHFPP 286_ PLPTP 291_ LDPEE 296_ TAYPS 301_ LSGGN 306_ STSNL 311_ THTMT 316_ HLGIS 321_ RGMGL 326_ GPGYD 331_ APGLH 336_ SPLSH 341_ PSLQS 346_ SLSNP 351_ NLQAS 356_ LSSPQ 361_ PQLQG 366_ SHSHP 371_ SLPAS 376_ SLARH 381_ VLPTT 386_ SLGHP 391_ SLSAP 396_ ALSSS 401_ SSSSS 406_ TSSPV 411_ LGAPS 416_ YPAST 421_ PGASP 426_ HHRRV 431_ PLSPL 436_ SLLAG 441_ PADAR 446_ RSQQQ 451_ LPKQF 456_ SPTMS 461_ PTLSS 466_ ITQGV 471_ PLDTS 476_ KLSTD 481_ QRLPP 486_ YPYSS 491_ PSLVL 496_ PTQPH 501_ TPKSL 506_ QQPGL 511_ PSQSC 516_ SVQSS 521_ GGQPP 526_ GRQSH 531_ YGTPY 536_ PPGPS 541_ GHGQQ 546_ SYHRP 551_ MSDFN 556_ LGNLE 561_ QFSME 566_ SPSAS 571_ LVLDP 576_ PGFSE 581_ GPGFL 586_ GGEGP 591_ MGGPQ 596_ DPHTF 601_ NHQNL 606_ THCSR 611_ HGSGP 616_ NIILT 621_ GDSSP 626_ GFSKE 631_ IAAAL 636_ AGVPG 641_ FEVSA 646_ AGLEL 651_ GLGLE 656_ DELRM 661_ EPLGL 666_ EGLNM 671_ LSDPC 676_ ALLPD 681_ PAVEE 686_SFRSD
1: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)