Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2)
1_MAAVL 6_ QRVER 11_ LSNRV 16_ VRVLG 21_ CNPGP 26_ MTLQG 31_ TNTYL 36_ VGTGP 41_ RRILI 46_ DTGEP 51_ AIPEY 56_ ISCLK 61_ QALTE 66_ FNTAI 71_ QEIVV 76_ THWHR 81_ DHSGG 86_ IGDIC 91_ KSINN 96_ DTTYC 101_ IKKLP 106_ RNPQR 111_ EEIIG 116_ NGEQQ 121_ YVYLK 126_ DGDVI 131_ KTEGA 136_ TLRVL 141_ YTPGH 146_ TDDHM 151_ ALLLE 156_ EENAI 161_ FSGDC 166_ ILGEG 171_ TTVFE 176_ DLYDY 181_ MNSLK 186_ ELLKI 191_ KADII 196_ YPGHG 201_ PVIHN 206_ AEAKI 211_ QQYIS 216_ HRNIR 221_ EQQIL 226_ TLFRE 231_ NFEKS 236_ FTVME 241_ LVKII 246_ YKNTP 251_ ENLHE 256_ MAKHN 261_ LLLHL 266_ KKLEK 271_ EGKIF 276_ SNTDP 281_DKKWK
1: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability