Gene name: CDCA8

Uniprot entry:

Q53HL2

Protein names:

Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein)

Protein sequence:

1_MAPRK 6_ GSSRV 11_ AKTNS 16_ LRRRK 21_ LASFL 26_ KDFDR 31_ EVEIR 36_ IKQIE 41_ SDRQN 46_ LLKEV 51_ DNLYN 56_ IEILR 61_ LPKAL 66_ REMNW 71_ LDYFA 76_ LGGNK 81_ QALEE 86_ AATAD 91_ LDITE 96_ INKLT 101_ AEAIQ 106_ TPLKS 111_ AKTRK 116_ VIQVD 121_ EMIVE 126_ EEEEE 131_ ENERK 136_ NLQTA 141_ RVKRC 146_ PPSKK 151_ RTQSI 156_ QGKGK 161_ GKRSS 166_ RANTV 171_ TPAVG 176_ RLEVS 181_ MVKPT 186_ PGLTP 191_ RFDSR 196_ VFKTP 201_ GLRTP 206_ AAGER 211_ IYNIS 216_ GNGSP 221_ LADSK 226_ EIFLT 231_ VPVGG 236_ GESLR 241_ LLASD 246_ LQRHS 251_ IAQLD 256_ PEALG 261_ NIKKL 266_ SNRLA 271_QICSS

Protein annotations

Protein functions:

1: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment