Ras-related protein Rab-6D (Rab6-like protein WTH3DI)
1_MSAGG 6_ DFGNP 11_ LRKFK 16_ LVFLG 21_ EQSVA 26_ KTSLI 31_ TRFRY 36_ DSFDN 41_ TYQAI 46_ IGIDF 51_ LSKTM 56_ YLEDG 61_ TIGLR 66_ LWDTA 71_ GQERL 76_ RSLIP 81_ RYIRD 86_ SAAAV 91_ VVYDI 96_ TNVNS 101_ FQQTT 106_ KWIDD 111_ VRTEG 116_ GSDVI 121_ ITLVG 126_ NKTDL 131_ ADKRQ 136_ VSIEE 141_ GERKA 146_ KGLNV 151_ TFIET 156_ RAKAG 161_ YNVKQ 166_ LFRRV 171_ AAALP 176_ GMEST 181_ QDGSR 186_ EDMSD 191_ IKLEK 196_ PQEQT 201_ VSEGG 206_ CSCYS 211_ PMSSS 216_ TLPQK 221_ PPYSF 226_ IDCSV 231_ NIGLN 236_ LFPSL 241_ ITFCN 246_SSLLP
1: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion