Gene name: C2CD6

Uniprot entry:

Q53TS8

Protein names:

C2 calcium-dependent domain-containing protein 6 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein)

Protein sequence:

1_MEPPQ 6_ ETNRP 11_ FSTLD 16_ NRSGQ 21_ VQVLS 26_ ATPLL 31_ QRNPY 36_ SSPDI 41_ MHIKG 46_ SEASS 51_ VPYAL 56_ NQGTT 61_ ALPKN 66_ KNQEG 71_ TGHRL 76_ LNMLR 81_ KTLKE 86_ SDSEE 91_ LEITQ 96_ ETPNL 101_ VPFGD 106_ VVGCL 111_ GIHIK 116_ NCRHF 121_ MPKIS 126_ LQHYA 131_ NLFIR 136_ ISINK 141_ AVKCT 146_ KMCSL 151_ LSKND 156_ EKNTV 161_ IKFDE 166_ VKYFS 171_ VQVPR 176_ RYDDK 181_ RNNIL 186_ LELIQ 191_ YDNRE 196_ KRAFL 201_ LGSVQ 206_ IHLYE 211_ VIQKG 216_ CFIEE 221_ VQVLH 226_ GNIFV 231_ CRLEV 236_ EFMFS 241_ YGNFG 246_ YGFSH 251_ QLKPL 256_ QKITE 261_ PSMFM 266_ NLAPP 271_ PERTD 276_ PVTKV 281_ ITPQT 286_ VEYPA 291_ FLSPD 296_ LNVTV 301_ GTPAV 306_ QSSNQ 311_ PSVVR 316_ LEKLQ 321_ QQPRE 326_ RLEKM 331_ KKEYR 336_ NLNTW 341_ IDKAN 346_ YLESI 351_ LMPKL 356_ EHKDS 361_ EETNI 366_ DEASE 371_ NTKSN 376_ HPEEE 381_ LENIV 386_ GVDIP 391_ LVNEE 396_ AETTA 401_ NELLD 406_ NDSEK 411_ GLTIP 416_ TLNQS 421_ DQDNS 426_ TADAS 431_ KNDES 436_ TPSPT 441_ EVHSL 446_ CTISN 451_ QETIK 456_ AGRIP 461_ PLGER 466_ QSESM 471_ PDRKM 476_ KNVFF 481_ PLEVK 486_ LKDNY 491_ PSILK 496_ ADSSL 501_ SEVAF 506_ SPKEY 511_ NSPSF 516_ RPEYI 521_ EFKPK 526_ FQDCS 531_ DKFED 536_ LHDMT 541_ SFTHL 546_ KKVKS 551_ RSRLL 556_ GKSSD 561_ DIHNH 566_ ARHSA 571_ RPYTA 576_ PEVNK 581_ QRESY 586_ SGKFT 591_ SRRMV 596_ SSGLV 601_ HINDK 606_ TSDYE 611_ MHKMR 616_PKKIK

Protein annotations

Protein functions:

1: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains. Targets the preassembled CatSper complexes to elongating flagella, where it links the channel-carrying vesicles and motor proteins