Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12)
1_MLQLL 6_ VLKIE 11_ DPGCF 16_ WVIIK 21_ GCSPF 26_ LDHDV 31_ DYQKL 36_ NSAMN 41_ DFYNS 46_ TCQDI 51_ EIKPL 56_ TLEEG 61_ QVCVV 66_ YCEEL 71_ KCWCR 76_ AIVKS 81_ ITSSA 86_ DQYLA 91_ ECFLV 96_ DFAKN 101_ IPVKS 106_ KNIRV 111_ VVESF 116_ MQLPY 121_ RAKKF 126_ SLYCT 131_ KPVTL 136_ HIDFC 141_ RDSTD 146_ IVPAK 151_ KWDNA 156_ AIQYF 161_ QNLLK 166_ ATTQV 171_ EARLC 176_ AVEED 181_ TFEVY 186_ LYVTI 191_ KDEKV 196_ CVNDD 201_ LVAKN 206_ YACYM 211_ SPTKN 216_ KNLDY 221_ LEKPR 226_ LNIKS 231_ APSFN 236_ KLNPA 241_ LTLWP 246_ MFLQG 251_ KDVQG 256_ MEDSH 261_ GVNFP 266_ AQSLQ 271_ HTWCK 276_ GIVGD 281_ LRPTA 286_ TAQDK 291_ AVKCN 296_ MDSLR 301_ DSPKD 306_ KSEKK 311_ HHCIS 316_ LKDTN 321_ KRVES 326_ SVYWP 331_ AKRGI 336_ TIYAD 341_ PDVPE 346_ ASALS 351_ QKSNE 356_ KPLRL 361_ TEKKE 366_ YDEKN 371_ SCVKL 376_ LQFLN 381_ PDPLR 386_ ADGIS 391_ DLQQL 396_ QKLKG 401_ LQPPV 406_ VVLRN 411_ KIKPC 416_ LTIDS 421_ SPLSA 426_ DLKKA 431_ LQRNK 436_ FPGPS 441_ HTESY 446_ SWPPI 451_ ARGCD 456_ VVVIS 461_ HCESN 466_ PLLYL 471_ LPVLT 476_ VLQTG 481_ ACYKS 486_ LPSRN 491_ GPLAV 496_ IVCPG 501_ WKKAQ 506_ FIFEL 511_ LGEYS 516_ MSSRP 521_ LHPVL 526_ LTIGL 531_ HKEEA 536_ KNTKL 541_ PRGCD 546_ VIVTT 551_ PYSLL 556_ RLLAC 561_ QSLLF 566_ LRLCH 571_ LILDE 576_ VEVLF 581_ LEANE 586_ QMFAI 591_ LDNFK 596_ KNIEV 601_ EERES 606_ APHQI 611_ VAVGV 616_ HWNKH 621_ IEHLI 626_ KEFMN 631_ DPYIV 636_ ITAME 641_ EAALY 646_ GNVQQ 651_ VVHLC 656_ LECEK 661_ TSSLL 666_ QALDF 671_ IPSQA 676_ QKTLI 681_ FTCSV 686_ AETEI 691_ VCKVV 696_ ESSSI 701_ FCLKM 706_ HKEMI 711_ FNLQN 716_ VLEQW 721_ KKKLS 726_ SGSQI 731_ ILALT 736_ DDCVP 741_ LLAIT 746_ DATCV 751_ IHFSF 756_ PASPK 761_ VFGGR 766_ LYCMS 771_ DHFHA 776_ EQGSP 781_ AEQGD 786_ KKAKS 791_ VLLLT 796_ EKDAS 801_ HAVGV 806_ LRYLE 811_ RADAK 816_ VPAEL 821_ YEFTA 826_ GVLEA 831_ KEDKK 836_ AGRPL 841_ CPYLK 846_ AFGFC 851_ KDKRI 856_ CPDRH 861_ RINPE 866_ TDLPR 871_ KLSSQ 876_ ALPSF 881_ GYIKI 886_ IPFYI 891_ LNATN 896_ YFGRI 901_ VDKHM 906_ DLYAT 911_ LNAEM 916_ NEYFK 921_ DSNKT 926_ TVEKV 931_ EKFGL 936_ YGLAE 941_ KTLFH 946_ RVQVL 951_ EVNQK 956_ EDAWA 961_ LDDIL 966_ VEFID 971_ EGRTG 976_ LVTRD 981_ QLLHL 986_ PEHFH 991_ TLPPQ 996_ AVEFI 1001_ VCRVK 1006_ PADNE 1011_ IEWNP 1016_ KVTRY 1021_ IHHKI 1026_ VGKLH 1031_ DAKVI 1036_ LALGN 1041_ TVWID 1046_ PMVHI 1051_ TNLSS 1056_ LKTSV 1061_ IDYNV 1066_ RAEIL 1071_ SMGMG 1076_ IDNPE 1081_ HIEQL 1086_ KKLRE 1091_ DAKIP 1096_ ACEES 1101_ LSQTP 1106_ PRVTG 1111_ TSPAQ 1116_ DQDHP 1121_ SEEQG 1126_ GQGTP 1131_ PAEDA 1136_ ACLQS 1141_ PQPED 1146_ TGAEG 1151_ GAESK 1156_ TSSEN 1161_ QKPGG 1166_ YLVFK 1171_RWLSS
1: Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs