Gene name: PIERCE1

Uniprot entry:

Q5BN46

Protein names:

Piercer of microtubule wall 1 protein (Pierce1) (UPF0691 protein C9orf116) (p53-induced expression in RB-null cells protein 1)

Protein sequence:

1_MAEEC 6_ PRACA 11_ EPVAP 16_ KATAP 21_ PERTS 26_ DYYRV 31_ SADLP 36_ GRFNN 41_ PGWFR 46_ GYRTQ 51_ KAVSV 56_ YRTSN 61_ QAYGS 66_ RAPTV 71_ HEMPK 76_ VFYPN 81_ SNKFS 86_ QQLAA 91_ GGMFR 96_ NNTLN 101_ VYLEK 106_ SIVTG 111_ PDNCI 116_ TSCDR 121_ LNFHP 126_ SYNIN 131_RPSIC

Protein annotations

Protein functions:

1: Microtubule inner protein involved in the attachment of outer dynein arms (ODAs) to dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). Functions at the initial step of left-right asymmetry specification of the visceral organs