RILP-like protein 1 (Rab-interacting lysosomal-like protein 1)
1_MEEER 6_ GSALA 11_ AESAL 16_ EKNVA 21_ ELTVM 26_ DVYDI 31_ ASLVG 36_ HEFER 41_ VIDQH 46_ GCEAI 51_ ARLMP 56_ KVVRV 61_ LEILE 66_ VLVSR 71_ HHVAP 76_ ELDEL 81_ RLELD 86_ RLRLE 91_ RMDRI 96_ EKERK 101_ HQKEL 106_ ELVED 111_ VWRGE 116_ AQDLL 121_ SQIAQ 126_ LQEEN 131_ KQLMT 136_ NLSHK 141_ DVNFS 146_ EEEFQ 151_ KHEGM 156_ SERER 161_ QVMKK 166_ LKEVV 171_ DKQRD 176_ EIRAK 181_ DRELG 186_ LKNED 191_ VEALQ 196_ QQQTR 201_ LMKIN 206_ HDLRH 211_ RVTVV 216_ EAQGK 221_ ALIEQ 226_ KVELE 231_ ADLQT 236_ KEQEM 241_ GSLRA 246_ ELGKL 251_ RERLQ 256_ GEHSQ 261_ NGEEE 266_ PETEP 271_ VGEES 276_ ISDAE 281_ KVAMD 286_ LKDPN 291_ RPRFT 296_ LQELR 301_ DVLHE 306_ RNELK 311_ SKVFL 316_ LQEEL 321_ AYYKS 326_ EEMEE 331_ ENRIP 336_ QPPPI 341_ AHPRT 346_ SPQPE 351_ SGIKR 356_ LFSFF 361_ SRDKK 366_ RLANT 371_ QRNVH 376_ IQESF 381_ GQWAN 386_ THRDD 391_ GYTEQ 396_GQEAL
1: Plays a role in the regulation of cell shape and polarity (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148)