Gene name: TMEM196

Uniprot entry:

Q5HYL7

Protein names:

Transmembrane protein 196

Protein sequence:

1_MCTSG 6_ QIIGS 11_ LLVLS 16_ VLEIG 21_ LGVSS 26_ VAVGA 31_ VSFSL 36_ ALREH 41_ KPQLG 46_ DSSPV 51_ WSGVC 56_ FLLCG 61_ ICGIL 66_ CAKKK 71_ SGLVM 76_ ILFSA 81_ CCICG 86_ LIGGI 91_ LNFQF 96_ LRAVT 101_ KKTSS 106_ LYPLH 111_ LASMS 116_ LACIG 121_ IGGCT 126_ LSSWL 131_ TCRLA 136_ SYEQR 141_ RMFSE 146_ REHSL 151_ HHSHE 156_ MAEKE 161_ ITDNM 166_ SNGGP 171_QLIFN

Protein annotations

Protein functions:

1: Acts as a tumor suppressor in lung cancer (PubMed:26056045, PubMed:36355209). Inhibits tumor cell growth by inhibiting cell proliferation and migration and promoting cell apoptosis (PubMed:26056045, PubMed:36355209). Inhibits metastasis of lung cancer by suppressing beta-catenin expression in the Wnt/beta-catenin signaling pathway (By similarity)