Krueppel-like factor 17 (Zinc finger protein 393)
1_MYGRP 6_ QAEME 11_ QEAGE 16_ LSRWQ 21_ AAHQA 26_ AQDNE 31_ NSAPI 36_ LNMSS 41_ SSGSS 46_ GVHTS 51_ WNQGL 56_ PSIQH 61_ FPHSA 66_ EMLGS 71_ PLVSV 76_ EAPGQ 81_ NVNEG 86_ GPQFS 91_ MPLPE 96_ RGMSY 101_ CPQAT 106_ LTPSR 111_ MIYCQ 116_ RMSPP 121_ QQEMT 126_ IFSGP 131_ QLMPV 136_ GEPNI 141_ PRVAR 146_ PFGGN 151_ LRMPP 156_ NGLPV 161_ SASTG 166_ IPIMS 171_ HTGNP 176_ PVPYP 181_ GLSTV 186_ PSDET 191_ LLGPT 196_ VPSTE 201_ AQAVL 206_ PSMAQ 211_ MLPPQ 216_ DAHDL 221_ GMPPA 226_ ESQSL 231_ LVLGS 236_ QDSLV 241_ SQPDS 246_ QEGPF 251_ LPEQP 256_ GPAPQ 261_ TVEKN 266_ SRPQE 271_ GTGRR 276_ GSSEA 281_ RPYCC 286_ NYENC 291_ GKAYT 296_ KRSHL 301_ VSHQR 306_ KHTGE 311_ RPYSC 316_ NWESC 321_ SWSFF 326_ RSDEL 331_ RRHMR 336_ VHTRY 341_ RPYKC 346_ DQCSR 351_ EFMRS 356_ DHLKQ 361_ HQKTH 366_ RPGPS 371_ DPQAN 376_ NNNGE 381_QDSPP
1: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity)