Gene name: COA6

Uniprot entry:

Q5JTJ3

Protein names:

Cytochrome c oxidase assembly factor 6 homolog

Protein sequence:

1_MGPGG 6_ PLLSP 11_ SRGFL 16_ LCKTG 21_ WHSNR 26_ LLGDC 31_ GPHTP 36_ VSTAL 41_ SFIAV 46_ GMAAP 51_ SMKER 56_ QVCWG 61_ ARDEY 66_ WKCLD 71_ ENLED 76_ ASQCK 81_ KLRSS 86_ FESSC 91_ PQQWI 96_ KYFDK 101_ RRDYL 106_ KFKEK 111_ FEAGQ 116_FEPSE

Protein annotations

Protein functions:

1: Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV