Gene name: MIIP

Uniprot entry:

Q5JXC2

Protein names:

Migration and invasion-inhibitory protein (IGFBP2-binding protein) (Invasion-inhibitory protein 45) (IIp45)

Protein sequence:

1_MVEAE 6_ ELAQL 11_ RLLNL 16_ ELLRQ 21_ LWVGQ 26_ DAVRR 31_ SVARA 36_ ASESS 41_ LESSS 46_ SYNSE 51_ TPSTP 56_ ETSST 61_ SLSTS 66_ CPRGR 71_ SSVWG 76_ PPDAC 81_ RGDLR 86_ DVARS 91_ GVASL 96_ PPAKC 101_ QHQES 106_ LGRPR 111_ PHSAP 116_ SLGTS 121_ SLRDP 126_ EPSGR 131_ LGDPG 136_ PQEAQ 141_ TPRSI 146_ LAQQS 151_ KLSKP 156_ RVTFS 161_ EESAV 166_ PKRSW 171_ RLRPY 176_ LGYDW 181_ IAGSL 186_ DTSSS 191_ ITSQP 196_ EAFFS 201_ KLQEF 206_ RETNK 211_ EECIC 216_ SHPEP 221_ QLPGL 226_ RESSG 231_ SGVEE 236_ DHECV 241_ YCYRV 246_ NRRLF 251_ PVPVD 256_ PGTPC 261_ RLCRT 266_ PRDQQ 271_ GPGTL 276_ AQPAH 281_ VRVSI 286_ PLSIL 291_ EPPHR 296_ YHIHR 301_ RKSFD 306_ ASDTL 311_ ALPRH 316_ CLLGW 321_ DIFPP 326_ KSEKS 331_ SAPRN 336_ LDLWS 341_ SVSAE 346_ AQHQK 351_ LSGTS 356_ SPFHP 361_ ASPMQ 366_ MLPPT 371_ PTWSV 376_ PQVPR 381_PHVPR

Protein annotations

Protein functions:

1: Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion