Cytochrome c oxidase assembly protein COX20, mitochondrial
1_MAAPP 6_ EPGEP 11_ EERKS 16_ LKLLG 21_ FLDVE 26_ NTPCA 31_ RHSIL 36_ YGSLG 41_ SVVAG 46_ FGHFL 51_ FTSRI 56_ RRSCD 61_ VGVGG 66_ FILVT 71_ LGCWF 76_ HCRYN 81_ YAKQR 86_ IQERI 91_ AREEI 96_ KKKIL 101_ YEGTH 106_ LDPER 111_KHNGS
1: Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:23125284). Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme (PubMed:24403053)