Transmembrane protein 201 (Spindle-associated membrane protein 1)
1_MEGVS 6_ ALLAR 11_ CPTAG 16_ LAGGL 21_ GVTAC 26_ AAAGV 31_ LLYRI 36_ ARRMK 41_ PTHTM 46_ VNCWF 51_ CNQDT 56_ LVPYG 61_ NRNCW 66_ DCPHC 71_ EQYNG 76_ FQENG 81_ DYNKP 86_ IPAQY 91_ LEHLN 96_ HVVSS 101_ APSLR 106_ DPSQP 111_ QQWVS 116_ SQVLL 121_ CKRCN 126_ HHQTT 131_ KIKQL 136_ AAFAP 141_ REEGR 146_ YDEEV 151_ EVYRH 156_ HLEQM 161_ YKLCR 166_ PCQAA 171_ VEYYI 176_ KHQNR 181_ QLRAL 186_ LLSHQ 191_ FKRRE 196_ ADQTH 201_ AQNFS 206_ SAVKS 211_ PVQVI 216_ LLRAL 221_ AFLAC 226_ AFLLT 231_ TALYG 236_ ASGHF 241_ APGTT 246_ VPLAL 251_ PPGGN 256_ GSATP 261_ DNGTT 266_ PGAEG 271_ WRQLL 276_ GLLPE 281_ HMAEK 286_ LCEAW 291_ AFGQS 296_ HQTGV 301_ VALGL 306_ LTCLL 311_ AMLLA 316_ GRIRL 321_ RRIDA 326_ FCTCL 331_ WALLL 336_ GLHLA 341_ EQHLQ 346_ AASPS 351_ WLDTL 356_ KFSTT 361_ SLCCL 366_ VGFTA 371_ AVATR 376_ KATGP 381_ RRFRP 386_ RRFFP 391_ GDSAG 396_ LFPTS 401_ PSLAI 406_ PHPSV 411_ GGSPA 416_ SLFIP 421_ SPPSF 426_ LPLAN 431_ QQLFR 436_ SPRRT 441_ SPSSL 446_ PGRLS 451_ RALSL 456_ GTIPS 461_ LTRAD 466_ SGYLF 471_ SGSRP 476_ PSQVS 481_ RSGEF 486_ PVSDY 491_ FSLLS 496_ GSCPS 501_ SPLPS 506_ PAPSV 511_ AGSVA 516_ SSSGS 521_ LRHRR 526_ PLISP 531_ ARLNL 536_ KGQKL 541_ LLFPS 546_ PPGEA 551_ PTTPS 556_ SSDEH 561_ SPHNG 566_ SLFTM 571_ EPPHV 576_ PRKPP 581_ LQDVK 586_ HALDL 591_ RSKLE 596_ RGSAC 601_ SNRSI 606_ KKEDD 611_ SSQSS 616_ TCVVD 621_ TTTRG 626_ CSEEA 631_ ATWRG 636_ RFGPS 641_ LVRGL 646_ LAVSL 651_ AANAL 656_ FTSVF 661_LYQSL
1: Critical regulator of angiogenesis and endothelial cell (EC) migration (PubMed:35311970). Promotes the migration of endothelial cells, which is essential for angiogenesis (PubMed:35311970). Interacts with the linker of nucleoskeleton and cytoskeleton (LINC) complex, which plays a vital role in connecting the cell's cytoskeleton to the nuclear envelope (PubMed:35311970). This interaction is essential for maintaining cellular structure and facilitating the movement of endothelial cells, which is critical for proper vascular development (PubMed:35311970). Involved in nuclear movement during fibroblast polarization and migration (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery (PubMed:27541860)
2: May define a distinct membrane domain in the vicinity of the mitotic spindle (PubMed:19494128). Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina (PubMed:21610090)