Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30)
1_MSALN 6_ WKPFV 11_ YGGLA 16_ SITAE 21_ CGTFP 26_ IDLTK 31_ TRLQI 36_ QGQTN 41_ DAKFK 46_ EIRYR 51_ GMLHA 56_ LVRIG 61_ REEGL 66_ KALYS 71_ GIAPA 76_ MLRQA 81_ SYGTI 86_ KIGTY 91_ QSLKR 96_ LFIER 101_ PEDET 106_ LPINV 111_ ICGIL 116_ SGVIS 121_ STIAN 126_ PTDVL 131_ KIRMQ 136_ AQSNT 141_ IQGGM 146_ IGNFM 151_ NIYQQ 156_ EGTRG 161_ LWKGV 166_ SLTAQ 171_ RAAIV 176_ VGVEL 181_ PVYDI 186_ TKKHL 191_ ILSGL 196_ MGDTV 201_ YTHFL 206_ SSFTC 211_ GLAGA 216_ LASNP 221_ VDVVR 226_ TRMMN 231_ QRVLR 236_ DGRCS 241_ GYTGT 246_ LDCLL 251_ QTWKN 256_ EGFFA 261_ LYKGF 266_ WPNWL 271_ RLGPW 276_ NIIFF 281_ VTYEQ 286_LKKLD
1: Antiporter that transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate (PubMed:31356773). The sulfate/sulfate exchange is much higher than the phosphate/phosphate and malate/malate exchanges (PubMed:31356773). The transport affinities is higher for sulfate and thiosulfate than for any other substrate (PubMed:31356773). May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also may mediate a very low unidirectional transport of sulfate, phosphate and (S)-malate (PubMed:31356773)