Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9)
1_MADSG 6_ LLLKR 11_ GSCRS 16_ TWLRV 21_ RKARP 26_ QLILS 31_ RRPRR 36_ RLGSL 41_ RWCGR 46_ RRLRW 51_ RLLQA 56_ QASGV 61_ DWREG 66_ ARQVS 71_ RAAAA 76_ RRPNT 81_ ATPSP 86_ IPSPT 91_ PASEP 96_ ESEPE 101_ LESAS 106_ SCHRP 111_ LLIPP 116_ VRPVG 121_ PGRAL 126_ LLLPV 131_ EQGFT 136_ FSGIC 141_ RVTCL 146_ YGQVQ 151_ VFGFT 156_ ISQGQ 161_ PAQDI 166_ FSVYT 171_ HSCLS 176_ IHALH 181_ YSQPE 186_ KSKKE 191_ LKREA 196_ RNLLK 201_ SHLNL 206_ DDRRW 211_ SMQNF 216_ SPQCS 221_ IVLLE 226_ HLKTA 231_ TVNFI 236_ TSYPG 241_ SSYIF 246_ VQESP 251_ TPQIK 256_ PEYLA 261_ LRSVG 266_ IRREK 271_ KRKGL 276_ QLTES 281_ TLSAL 286_ EELVN 291_ VSCEE 296_ VDGCP 301_ VILVC 306_ GSQDV 311_ GKSTF 316_ NRYLI 321_ NHLLN 326_ SLPCV 331_ DYLEC 336_ DLGQT 341_ EFTPP 346_ GCISL 351_ LNITE 356_ PVLGP 361_ PFTHL 366_ RTPQK 371_ MVYYG 376_ KPSCK 381_ NNYEN 386_ YIDIV 391_ KYVFS 396_ AYKRE 401_ SPLIV 406_ NTMGW 411_ VSDQG 416_ LLLLI 421_ DLIRL 426_ LSPSH 431_ VVQFR 436_ SDHSK 441_ YMPDL 446_ TPQYV 451_ DDMDG 456_ LYTKS 461_ KTKMR 466_ NRRFR 471_ LAAFA 476_ DALEF 481_ ADEEK 486_ ESPVE 491_ FTGHK 496_ LIGVY 501_ TDFAF 506_ RITPR 511_ NRESH 516_ NKILR 521_ DLSIL 526_ SYLSQ 531_ LQPPM 536_ PKPLS 541_ PLHSL 546_ TPYQV 551_ PFNAV 556_ ALRIT 561_ HSDVA 566_ PTHIL 571_ YAVNA 576_ SWVGL 581_ CKIQD 586_ DVRGY 591_ TNGPI 596_ LLAQT 601_ PICDC 606_ LGFGI 611_ CRGID 616_ MEKRL 621_ YHILT 626_ PVPPE 631_ ELRTV 636_ NCLLV 641_ GAIAI 646_ PHCVL 651_ KCQRG 656_ IEGTV 661_ PYVTT 666_ DYNFK 671_ LPGAS 676_ EKIGA 681_ REPEE 686_ AHKEK 691_ PYRRP 696_KFCRK
1: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of single-stranded and double-stranded RNA and DNA substrates (PubMed:21063389). Involved in rRNA processing and its kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form (PubMed:21063389). Required for the efficient pre-rRNA processing of internal transcribed spacer 2 (ITS2) (PubMed:21063389). Associates with LAS1L to form an ITS2 pre-rRNA endonuclease-kinase complex and is responsible for the transport of this complex into the nucleolus (PubMed:31288032)