Gene name: TMEM170B

Uniprot entry:

Q5T4T1

Protein names:

Transmembrane protein 170B

Protein sequence:

1_MKAEG 6_ GDHSM 11_ INLSV 16_ QQVLS 21_ LWAHG 26_ TVLRN 31_ LTEMW 36_ YWIFL 41_ WALFS 46_ SLFVH 51_ GAAGV 56_ LMFVM 61_ LQRHR 66_ QGRVI 71_ SVIAV 76_ SIGFL 81_ ASVTG 86_ AMITS 91_ AAVAG 96_ IYRVA 101_ GKNMA 106_ PLEAL 111_ VWGVG 116_ QTVLT 121_ LIISF 126_SRILA

Protein annotations

Protein functions:

1: Negatively regulates the canonical Wnt signaling in breast cancer cells. Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets (PubMed:29367600)