Gene name: ARTN

Uniprot entry:

Q5T4W7

Protein names:

Artemin (Enovin) (Neublastin)

Protein sequence:

1_MELGL 6_ GGLST 11_ LSHCP 16_ WPRQQ 21_ PALWP 26_ TLAAL 31_ ALLSS 36_ VAEAS 41_ LGSAP 46_ RSPAP 51_ REGPP 56_ PVLAS 61_ PAGHL 66_ PGGRT 71_ ARWCS 76_ GRARR 81_ PPPQP 86_ SRPAP 91_ PPPAP 96_ PSALP 101_ RGGRA 106_ ARAGG 111_ PGSRA 116_ RAAGA 121_ RGCRL 126_ RSQLV 131_ PVRAL 136_ GLGHR 141_ SDELV 146_ RFRFC 151_ SGSCR 156_ RARSP 161_ HDLSL 166_ ASLLG 171_ AGALR 176_ PPPGS 181_ RPVSQ 186_ PCCRP 191_ TRYEA 196_ VSFMD 201_ VNSTW 206_ RTVDR 211_LSATA

Protein annotations

Protein functions:

1: Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain (PubMed:10583383, PubMed:9883723). Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor (PubMed:31535977). Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue (By similarity)