Gene name: LCE3C

Uniprot entry:

Q5T5A8

Protein names:

Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A)

Protein sequence:

1_MSCQQ 6_ NQQQC 11_ QPPPS 16_ CPSPK 21_ CPPKS 26_ PAQCL 31_ PPPSS 36_ DCALS 41_ SGGCG 46_ PSSES 51_ GCCLS 56_ HHRHF 61_ RSHQC 66_ RRQRS 71_ NSCDR 76_ GSGQQ 81_ GGGSC 86_RGHGS

Protein annotations

Protein functions:

1: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035)