Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)
1_MAGAI 6_ IENMS 11_ TKKLC 16_ IVGGI 21_ LLVFQ 26_ IIAFL 31_ VGGLI 36_ APGPT 41_ TAVSY 46_ MSVKC 51_ VDARK 56_ NHHKT 61_ KWFVP 66_ WGPNH 71_ CDKIR 76_ DIEEA 81_ IPREI 86_ EANDI 91_ VFSVH 96_ IPLPH 101_ MEMSP 106_ WFQFM 111_ LFILQ 116_ LDIAF 121_ KLNNQ 126_ IRENA 131_ EVSMD 136_ VSLAY 141_ RDDAF 146_ AEWTE 151_ MAHER 156_ VPRKL 161_ KCTFT 166_ SPKTP 171_ EHEGR 176_ YYECD 181_ VLPFM 186_ EIGSV 191_ AHKFY 196_ LLNIR 201_ LPVNE 206_ KKKIN 211_ VGIGE 216_ IKDIR 221_ LVGIH 226_ QNGGF 231_ TKVWF 236_ AMKTF 241_ LTPSI 246_ FIIMV 251_ WYWRR 256_ ITMMS 261_ RPPVL 266_ LEKVI 271_ FALGI 276_ SMTFI 281_ NIPVE 286_ WFSIG 291_ FDWTW 296_ MLLFG 301_ DIRQG 306_ IFYAM 311_ LLSFW 316_ IIFCG 321_ EHMMD 326_ QHERN 331_ HIAGY 336_ WKQVG 341_ PIAVG 346_ SFCLF 351_ IFDMC 356_ ERGVQ 361_ LTNPF 366_ YSIWT 371_ TDIGT 376_ ELAMA 381_ FIIVA 386_ GICLC 391_ LYFLF 396_ LCFMV 401_ FQVFR 406_ NISGK 411_ QSSLP 416_ AMSKV 421_ RRLHY 426_ EGLIF 431_ RFKFL 436_ MLITL 441_ ACAAM 446_ TVIFF 451_ IVSQV 456_ TEGHW 461_ KWGGV 466_ TVQVN 471_ SAFFT 476_ GIYGM 481_ WNLYV 486_ FALMF 491_ LYAPS 496_ HKNYG 501_ EDQSN 506_ GDLGV 511_ HSGEE 516_ LQLTT 521_ TITHV 526_ DGPTE 531_ IYKLT 536_RKEAQ
1: Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins (PubMed:34587386). Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity)