Gene name: LCE3A

Uniprot entry:

Q5TA76

Protein names:

Late cornified envelope protein 3A (Late envelope protein 13)

Protein sequence:

1_MSCQQ 6_ NQQQC 11_ QPPPK 16_ CPAKS 21_ PAQCL 26_ PPASS 31_ SCAPS 36_ SGGCG 41_ PSSER 46_ SCCLS 51_ HHRCR 56_ RSHRC 61_ RCQSS 66_ NSCDR 71_ GSGQQ 76_ GGSSS 81_CGHSS

Protein annotations

Protein functions:

1: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035)