Late cornified envelope protein 3B (Late envelope protein 14)
1_MSCQQ 6_ NQQQC 11_ QPLPK 16_ CPSPK 21_ CPPKS 26_ SAQCL 31_ PPASS 36_ CCAPR 41_ PGCCG 46_ GPSSE 51_ GGCCL 56_ SHHRC 61_ CRSHR 66_ CRRQS 71_ SNSCD 76_ RGSGQ 81_ QDGAS 86_DCGYG
1: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035)