Ribonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B)
1_MAAGV 6_ DCGDG 11_ VGARQ 16_ HVFLV 21_ SEYLK 26_ DASKK 31_ MKNGL 36_ MFVKL 41_ VNPCS 46_ GEGAI 51_ YLFNM 56_ CLQQL 61_ FEVKV 66_ FKEKH 71_ HSWFI 76_ NQSVQ 81_ SGGLL 86_ HFATP 91_ VDPLF 96_ LLLHY 101_ LIKAD 106_ KEGKF 111_ QPLDQ 116_ VVVDN 121_ VFPNC 126_ ILLLK 131_ LPGLE 136_ KLLHH 141_ VTEEK 146_ GNPEI 151_ DNKKY 156_ YKYSK 161_ EKTLK 166_ WLEKK 171_ VNQTV 176_ AALKT 181_ NNVNV 186_ SSRVQ 191_ STAFF 196_ SGDQA 201_ STDKE 206_ EDYIR 211_ YAHGL 216_ ISDYI 221_ PKELS 226_ DDLSK 231_ YLKLP 236_ EPSAS 241_ LPNPP 246_ SKKIK 251_ LSDEP 256_ VEAKE 261_ DYTKF 266_ NTKDL 271_ KTEKK 276_ NSKMT 281_ AAQKA 286_ LAKVD 291_ KSGMK 296_ SIDTF 301_ FGVKN 306_KKKIG
1: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes