Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase)
1_MQCLA 6_ AALKD 11_ ETNMS 16_ GGGEQ 21_ ADILP 26_ ANYVV 31_ KDRWK 36_ VLKKI 41_ GGGGF 46_ GEIYE 51_ AMDLL 56_ TRENV 61_ ALKVE 66_ SAQQP 71_ KQVLK 76_ MEVAV 81_ LKKLQ 86_ GKDHV 91_ CRFIG 96_ CGRNE 101_ KFNYV 106_ VMQLQ 111_ GRNLA 116_ DLRRS 121_ QPRGT 126_ FTLST 131_ TLRLG 136_ KQILE 141_ SIEAI 146_ HSVGF 151_ LHRDI 156_ KPSNF 161_ AMGRL 166_ PSTYR 171_ KCYML 176_ DFGLA 181_ RQYTN 186_ TTGDV 191_ RPPRN 196_ VAGFR 201_ GTVRY 206_ ASVNA 211_ HKNRE 216_ MGRHD 221_ DLWSL 226_ FYMLV 231_ EFAVG 236_ QLPWR 241_ KIKDK 246_ EQVGM 251_ IKEKY 256_ EHRML 261_ LKHMP 266_ SEFHL 271_ FLDHI 276_ ASLDY 281_ FTKPD 286_ YQLIM 291_ SVFEN 296_ SMKER 301_ GIAEN 306_ EAFDW 311_ EKAGT 316_ DALLS 321_ TSTST 326_ PPQQN 331_ TRQTA 336_ AMFGV 341_ VNVTP 346_ VPGDL 351_ LRENT 356_ EDVLQ 361_ GEHLS 366_ DQENA 371_ PPILP 376_ GRPSE 381_ GLGPS 386_ PHLVP 391_ HPGGP 396_ EAEVW 401_ EETDV 406_ NRNKL 411_ RINIG 416_ KSPCV 421_ EEEQS 426_ RGMGV 431_ PSSPV 436_ RAPPD 441_ SPTTP 446_ VRSLR 451_ YRRVN 456_ SPESE 461_ RLSTA 466_ DGRVE 471_ LPERR 476_ SRMDL 481_ PGSPS 486_ RQACS 491_ SQPAQ 496_ MLSVD 501_ TGHAD 506_ RQASG 511_ RMDVS 516_ ASVEQ 521_ EALSN 526_ AFRSV 531_ PLAEE 536_ EDFDS 541_ KEWVI 546_ IDKET 551_ ELKDF 556_ PPGAE 561_ PSTSG 566_ TTDEE 571_ PEELR 576_ PLPEE 581_ GEERR 586_ RLGAE 591_ PTVRP 596_ RGRSM 601_ QALAE 606_ EDLQH 611_ LPPQP 616_ LPPQL 621_ SQGDG 626_ RSETS 631_ QPPTP 636_ GSPSH 641_ SPLHS 646_ GPRPR 651_ RRESD 656_ PTGPQ 661_ RQVFS 666_ VAPPF 671_ EVNGL 676_ PRAVP 681_ LSLPY 686_ QDFKR 691_ DLSDY 696_ RERAR 701_ LLNRV 706_ RRVGF 711_ SHMLL 716_ TTPQV 721_ PLAPV 726_ QPQAN 731_ GKEEE 736_ EEEEE 741_ DEEEE 746_ EEDEE 751_ EEEEE 756_ EEEEE 761_ EEEEE 766_ EEEEE 771_ EAAAA 776_ VALGE 781_ VLGPR 786_ SGSSS 791_ EGSER 796_ STDRS 801_ QEGAP 806_ STLLA 811_ DDQKE 816_ SRGRA 821_ SMADG 826_ DLEPE 831_ EGSKT 836_ LVLVS 841_ PGDMK 846_ KSPVT 851_ AELAP 856_ DPDLG 861_ TLAAL 866_ TPQHE 871_ RPQPT 876_ GSQLD 881_ VSEPG 886_ TLSSV 891_ LKSEP 896_ KPPGP 901_ GAGLG 906_ AGTVT 911_ TGVGG 916_ VAVTS 921_ SPFTK 926_ VERTF 931_ VHIAE 936_ KTHLN 941_ VMSSG 946_ GQALR 951_ SEEFS 956_ AGGEL 961_ GLELA 966_ SDGGA 971_ VEEGA 976_ RAPLE 981_ NGLAL 986_ SGLNG 991_ AEIEG 996_ SALSG 1001_ APRET 1006_ PSEMA 1011_ TNSLP 1016_ NGPAL 1021_ ADGPA 1026_ PVSPL 1031_ EPSPE 1036_ KVATI 1041_ SPRRH 1046_ AMPGS 1051_ RPRSR 1056_ IPVLL 1061_ SEEDT 1066_ GSEPS 1071_ GSLSA 1076_ KERWS 1081_ KRARP 1086_ QQDLA 1091_ RLVME 1096_ KRQGR 1101_ LLLRL 1106_ ASGAS 1111_ SSSSE 1116_ EQRRA 1121_ SETLS 1126_ GTGSE 1131_ EDTPA 1136_ SEPAA 1141_ ALPRK 1146_ SGRAA 1151_ ATRSR 1156_ IPRPI 1161_ GLRMP 1166_ MPVAA 1171_ QQPAS 1176_ RSHGA 1181_ APALD 1186_ TAITS 1191_ RLQLQ 1196_ TPPGS 1201_ ATAAD 1206_ LRPKQ 1211_ PPGRG 1216_ LGPGR 1221_ AQAGA 1226_ RPPAP 1231_ RSPRL 1236_ PASTS 1241_ AARNA 1246_ SASPR 1251_ SQSLS 1256_ RRESP 1261_ SPSHQ 1266_ ARPGV 1271_ PPPRG 1276_ VPPAR 1281_ AQPDG 1286_ TPSPG 1291_ GSKKG 1296_ PRGKL 1301_ QAQRA 1306_ TTKGR 1311_ AGGAE 1316_GRAGA
1: Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU