Protein THEMIS2 (Induced by contact to basement membrane 1 protein) (Protein ICB-1) (Thymocyte-expressed molecule involved in selection protein 2)
1_MEPVP 6_ LQDFV 11_ RALDP 16_ ASLPR 21_ VLRVC 26_ SGVYF 31_ EGSIY 36_ EISGN 41_ ECCLS 46_ TGDLI 51_ KVTQV 56_ RLQKV 61_ VCENP 66_ KTSQT 71_ MELAP 76_ NFQGY 81_ FTPLN 86_ TPQSY 91_ ETLEE 96_ LVSAT 101_ TQSSK 106_ QLPTC 111_ FMSTH 116_ RIVTE 121_ GRVVT 126_ EDQLL 131_ MLEAV 136_ VMHLG 141_ IRSAR 146_ CVLGM 151_ EGQQV 156_ ILHLP 161_ LSQKG 166_ PFWTW 171_ EPSAP 176_ RTLLQ 181_ VLQDP 186_ ALKDL 191_ VLTCP 196_ TLPWH 201_ SLILR 206_ PQYEI 211_ QAIMH 216_ MRRTI 221_ VKIPS 226_ TLEVD 231_ VEDVT 236_ ASSRH 241_ VHFIK 246_ PLLLS 251_ EVLAW 256_ EGPFP 261_ LSMEI 266_ LEVPE 271_ GRPIF 276_ LSPWV 281_ GSLQK 286_ GQRLC 291_ VYGLA 296_ SPPWR 301_ VLASS 306_ KGRKV 311_ PRHFL 316_ VSGGY 321_ QGKLR 326_ RRPRE 331_ FPTAY 336_ DLLGA 341_ FQPGR 346_ PLRVV 351_ ATKDC 356_ EGERE 361_ ENPEF 366_ TSLAV 371_ GDRLE 376_ VLGPG 381_ QAHGA 386_ QGSDV 391_ DVLVC 396_ QRLSD 401_ QAGED 406_ EEEEC 411_ KEEAE 416_ SPERV 421_ LLPFH 426_ FPGSF 431_ VEEMS 436_ DSRRY 441_ SLADL 446_ TAQFS 451_ LPCEV 456_ KVVAK 461_ DTSHP 466_ TDPLT 471_ SFLGL 476_ RLEEK 481_ ITEPF 486_ LVVSL 491_ DSEPG 496_ MCFEI 501_ PPRWL 506_ DLTVV 511_ KAKGQ 516_ PDLPE 521_ GSLPI 526_ ATVEE 531_ LTDTF 536_ YYRLR 541_ KLPAC 546_ EIQAP 551_ PPRPP 556_ KNQGL 561_ SKQRR 566_ HSSEG 571_ GVKSS 576_ QVLGL 581_ QQHAR 586_ LPKPK 591_ AKTLP 596_ EFIKD 601_ GSSTY 606_ SKIPA 611_ HRKGH 616_ RPAKP 621_ QRQDL 626_ DDDEH 631_ DYEEI 636_LEQFQ
1: May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production (PubMed:20644716). Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity)