Probable E3 ubiquitin-protein ligase HECTD2 (EC 2.3.2.26) (HECT domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECTD2)
1_MSEAV 6_ RVPSP 11_ ATPLV 16_ VAAPA 21_ PEERK 26_ GKESE 31_ REKLP 36_ PIVSA 41_ GAGAT 46_ AGLDR 51_ GAKGQ 56_ ISTFS 61_ SFISA 66_ VSPKK 71_ EAAEN 76_ RSSPA 81_ HLVFP 86_ NIKNV 91_ REPPP 96_ ICLDV 101_ RQKQR 106_ TSMDA 111_ SSSEM 116_ KAPVL 121_ PEPIL 126_ PIQPK 131_ TVKDF 136_ QEDVE 141_ KVKSS 146_ GDWKA 151_ VHDFY 156_ LTTFD 161_ SFPEL 166_ NAAFK 171_ KDATA 176_ SFNTI 181_ EDSGI 186_ NAKFV 191_ NAVYD 196_ TLLNT 201_ PQDVQ 206_ KTVLK 211_ GIINS 216_ LLREW 221_ KGPRT 226_ KDDLR 231_ AYFIL 236_ LQNPQ 241_ FNNTS 246_ TYVIY 251_ AHLLR 256_ QIATL 261_ VEADH 266_ HFLVH 271_ WFKKL 276_ SQKRF 281_ KQLVE 286_ RLLQF 291_ ISLRL 296_ FPAKP 301_ EEFPP 306_ ITKCS 311_ WWIPS 316_ AAKVL 321_ ALLNT 326_ ANNLV 331_ HPPLI 336_ PYTDF 341_ YNSTL 346_ DHIDL 351_ MEEYH 356_ TWQNF 361_ GNSHR 366_ FSFCQ 371_ YPFVI 376_ SVAAK 381_ KIIIQ 386_ RDSEQ 391_ QMINI 396_ ARQSL 401_ VDKVS 406_ RRQRP 411_ DMNIL 416_ FLNMK 421_ VRRTH 426_ LVSDS 431_ LDELT 436_ RKRAD 441_ LKKKL 446_ KVTFV 451_ GEAGL 456_ DMGGL 461_ TKEWF 466_ LLLIR 471_ QIFHP 476_ DYGMF 481_ TYHKD 486_ SHCHW 491_ FSSFK 496_ CDNYS 501_ EFRLV 506_ GILMG 511_ LAVYN 516_ SITLD 521_ IRFPP 526_ CCYKK 531_ LLSPP 536_ IIPSD 541_ QNIPV 546_ GICNV 551_ TVDDL 556_ CQIMP 561_ ELAHG 566_ LSELL 571_ SHEGN 576_ VEEDF 581_ YSTFQ 586_ VFQEE 591_ FGIIK 596_ SYNLK 601_ PGGDK 606_ ISVTN 611_ QNRKE 616_ YVQLY 621_ TDFLL 626_ NKSIY 631_ KQFAA 636_ FYYGF 641_ HSVCA 646_ SNALM 651_ LLRPE 656_ EVEIL 661_ VCGSP 666_ DLDMH 671_ ALQRS 676_ TQYDG 681_ YAKTD 686_ LTIKY 691_ FWDVV 696_ LGFPL 701_ DLQKK 706_ LLHFT 711_ TGSDR 716_ VPVGG 721_ MADLN 726_ FKISK 731_ NETST 736_ NCLPV 741_ AHTCF 746_ NQLCL 751_ PPYKS 756_ KKDLK 761_ QKLII 766_ GISNS 771_EGFGL
1: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
2: (Microbial infection) Catalyzes ubiquitination of Botulinum neurotoxin A light chain (LC) of C.botulinum neurotoxin type A (BoNT/A)