Alpha/beta hydrolase domain-containing protein 17B (Abhydrolase domain-containing protein 17B) (EC 3.1.2.22)
1_MNNLS 6_ FSELC 11_ CLFCC 16_ PPCPG 21_ KIASK 26_ LAFLP 31_ PDPTY 36_ TLMCD 41_ ESGSR 46_ WTLHL 51_ SERAD 56_ WQYSS 61_ REKDA 66_ IECFM 71_ TRTSK 76_ GNRIA 81_ CMFVR 86_ CSPNA 91_ KYTLL 96_ FSHGN 101_ AVDLG 106_ QMSSF 111_ YIGLG 116_ SRINC 121_ NIFSY 126_ DYSGY 131_ GASSG 136_ KPTEK 141_ NLYAD 146_ IEAAW 151_ LALRT 156_ RYGIR 161_ PENVI 166_ IYGQS 171_ IGTVP 176_ SVDLA 181_ ARYES 186_ AAVIL 191_ HSPLT 196_ SGMRV 201_ AFPDT 206_ KKTYC 211_ FDAFP 216_ NIDKI 221_ SKITS 226_ PVLII 231_ HGTED 236_ EVIDF 241_ SHGLA 246_ LFERC 251_ QRPVE 256_ PLWVE 261_ GAGHN 266_ DVELY 271_ GQYLE 276_ RLKQF 281_VSQEL
1: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:26701913). Has depalmitoylating activity towards DLG4/PSD95 (PubMed:26701913). Has depalmitoylating activity towards GAP43 (By similarity). Has depalmitoylating activity towards MAP6 (By similarity). Has depalmitoylating activity towards NRAS (PubMed:26701913)