Gene name: MICOS13

Uniprot entry:

Q5XKP0

Protein names:

MICOS complex subunit MIC13 (Protein P117)

Protein sequence:

1_MVARV 6_ WSLMR 11_ FLIKG 16_ SVAGG 21_ AVYLV 26_ YDQEL 31_ LGPSD 36_ KSQAA 41_ LQKAG 46_ EVVPP 51_ AMYQF 56_ SQYVC 61_ QQTGL 66_ QIPQL 71_ PAPPK 76_ IYFPI 81_ RDSWN 86_ AGIMT 91_ VMSAL 96_ SVAPS 101_ KAREY 106_ SKEGW 111_EYVKA

Protein annotations

Protein functions:

1: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (PubMed:25997101, PubMed:27623147, PubMed:32567732). Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology (PubMed:25997101, PubMed:27623147, PubMed:32567732). Required for the incorporation of MICOS10/MIC10 into the MICOS complex (PubMed:25997101, PubMed:27623147)