F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor)
1_MENLE 6_ SRLKN 11_ APYFR 16_ CEKGT 21_ DSIPL 26_ CRKCE 31_ TCVLA 36_ WKIFS 41_ TKEWF 46_ CRIND 51_ ISQRR 56_ FLVGI 61_ LKQLN 66_ SLYLL 71_ HYFQN 76_ ILQTT 81_ QGKDF 86_ IYNRS 91_ RINLS 96_ KKEGK 101_ VVKSS 106_ LNQML 111_ DKTVE 116_ QKMKE 121_ ILYWF 126_ ANSTQ 131_ WTKAN 136_ YTLLL 141_ LQMCN 146_ PKLLL 151_ TAANV 156_ IRVLF 161_ LREEN 166_ NISGL 171_ NQDIT 176_ DVCFS 181_ PEKDH 186_ SSKSA 191_ TSQVY 196_ WTAKT 201_ QHTSL 206_ PLSKA 211_ PENEH 216_ LLGAA 221_ SNPEE 226_ PWRNS 231_ LRCIS 236_ EMNRL 241_ FSGKG 246_ DITKP 251_ GYDPC 256_ NLLVD 261_ LDDIR 266_ DLSSG 271_ FSKYR 276_ DFIRY 281_ LPIHL 286_ SKYIL 291_ RMLDR 296_ HTLNK 301_ CASVS 306_ QHWAA 311_ MAQQV 316_ KMDLS 321_ AHGFI 326_ QNQIT 331_ FLQGS 336_ YTRGI 341_ DPNYA 346_ NKVSI 351_ PVPKM 356_ VDDGK 361_ SMRVK 366_ HPKWK 371_ LRTKN 376_ EYNLW 381_ TAYQN 386_ EETQQ 391_ VLIEE 396_ RNVFC 401_ GTYNV 406_ RILSD 411_ TWDQN 416_ RVIHY 421_ SGGDL 426_ IAVSS 431_ NRKIH 436_ LLDII 441_ QVKAI 446_ PVEFR 451_ GHAGS 456_ VRALF 461_ LCEEE 466_ NFLLS 471_ GSYDL 476_ SIRYW 481_ DLKSG 486_ VCTRI 491_ FGGHQ 496_ GTITC 501_ MDLCK 506_ NRLVS 511_ GGRDC 516_ QVKVW 521_ DVDTG 526_ KCLKT 531_ FRHKD 536_ PILAT 541_ RINDT 546_ YIVSS 551_ CERGL 556_ VKVWH 561_ IAMAQ 566_ LVKTL 571_ SGHEG 576_ AVKCL 581_ FFDQW 586_ HLLSG 591_ STDGL 596_ VMAWS 601_ MVGKY 606_ ERCLM 611_ AFKHP 616_ KEVLD 621_ VSLLF 626_ LRVIS 631_ ACADG 636_ KIRIY 641_ NFLNG 646_ NCMKV 651_ LKANG 656_ RGDPV 661_ LSFFI 666_ QGNRM 671_ VVNTE 676_ SNVLM 681_ FQFEH 686_ IKWQY 691_ AVEKT 696_ KQKKN 701_ KEKEE 706_ EKEEN 711_ SLMEI 716_ LSKCN 721_ IQVHS 726_ PRESV 731_ SSKQT 736_ VIQEL 741_ LPGKP 746_ PKSRV 751_ LLKPA 756_ KFSSA 761_ VLIEE 766_ LQSQG 771_ KSKSP 776_ RRDAD 781_ DVEKA 786_ QKQGQ 791_ LETPG 796_ KLPSH 801_ PKKKS 806_ WKIPM 811_ SPDQF 816_ LLTVS 821_ ALQHA 826_ HNSGE 831_ FAYPC 836_ RPQTE 841_ ITDVW 846_ GPSIS 851_ YPRKV 856_ LNFKG 861_ KSIQR 866_ AVDRL 871_ RLSNP 876_ PIDVK 881_ RTSIP 886_ LEIQK 891_ LQPNL 896_ KISLH 901_ SPRVQ 906_ STIPQ 911_ PMIIR 916_ SRFSG 921_ SLKGG 926_ DQVTS 931_ SIERA 936_ VCSTG 941_ PLTSM 946_ QVIKP 951_ NRMLA 956_ PQVGT 961_ ATLSL 966_ KKERP 971_ RIYTA 976_ LDPFR 981_ VNTEF 986_ VLLTV 991_ KEEKE 996_ HQEAK 1001_ MKEYQ 1006_ AREST 1011_ GVVDP 1016_ GKVSK 1021_ AAWIR 1026_ KIKGL 1031_ PIDNF 1036_ TKQGK 1041_ TAAPE 1046_LGQNV
1: Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1