Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
1_MMDVS 6_ GVGFP 11_ SKVPW 16_ KKMSA 21_ EELEN 26_ QYCPS 31_ RWVVR 36_ LGAEE 41_ ALRTY 46_ SQIGI 51_ EATTR 56_ ARATR 61_ KSLLH 66_ VPYGD 71_ GEGEK 76_ VDIYF 81_ PDESS 86_ EALPF 91_ FLFFH 96_ GGYWQ 101_ SGSKD 106_ ESAFM 111_ VHPLT 116_ AQGVA 121_ VVIVA 126_ YGIAP 131_ KGTLD 136_ HMVDQ 141_ VTRSV 146_ AFVQK 151_ RYPSN 156_ KGIYL 161_ CGHSA 166_ GAHLA 171_ AMMLL 176_ ADWTK 181_ HGVTP 186_ NLRGF 191_ FLVSG 196_ VFDLE 201_ PIVYT 206_ SQNVA 211_ LQLTL 216_ EDAQR 221_ NSPQL 226_ KVAQA 231_ QPVDP 236_ TCRVL 241_ VVVGQ 246_ FDSPE 251_ FHRQS 256_ WEFYQ 261_ TLCQG 266_ EWKAS 271_ FEELH 276_ DVDHF 281_ EIVEN 286_ LTQKD 291_ NVLTQ 296_IILKT
1: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites