Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase)
1_MSQGS 6_ PGDWA 11_ PLDPT 16_ PGPPA 21_ SPNPF 26_ VHELH 31_ LSRLQ 36_ RVKFC 41_ LLGAL 46_ LAPIR 51_ VLLAF 56_ IVLFL 61_ LWPFA 66_ WLQVA 71_ GLSEE 76_ QLQEP 81_ ITGWR 86_ KTVCH 91_ NGVLG 96_ LSRLL 101_ FFLLG 106_ FLRIR 111_ VRGQR 116_ ASRLQ 121_ APVLV 126_ AAPHS 131_ TFFDP 136_ IVLLP 141_ CDLPK 146_ VVSRA 151_ ENLSV 156_ PVIGA 161_ LLRFN 166_ QAILV 171_ SRHDP 176_ ASRRR 181_ VVEEV 186_ RRRAT 191_ SGGKW 196_ PQVLF 201_ FPEGT 206_ CSNKK 211_ ALLKF 216_ KPGAF 221_ IAGVP 226_ VQPVL 231_ IRYPN 236_ SLDTT 241_ SWAWR 246_ GPGVL 251_ KVLWL 256_ TASQP 261_ CSIVD 266_ VEFLP 271_ VYHPS 276_ PEESR 281_ DPTLY 286_ ANNVQ 291_ RVMAQ 296_ ALGIP 301_ ATECE 306_ FVGSL 311_ PVIVV 316_ GRLKV 321_ ALEPQ 326_ LWELG 331_ KVLRK 336_ AGLSA 341_ GYVDA 346_ GAEPG 351_ RSRMI 356_ SQEEF 361_ ARQLQ 366_ LSDPQ 371_ TVAGA 376_ FGYFQ 381_ QDTKG 386_ LVDFR 391_ DVALA 396_ LAALD 401_ GGRSL 406_ EELTR 411_ LAFEL 416_ FAEEQ 421_ AEGPN 426_ RLLYK 431_ DGFST 436_ ILHLL 441_ LGSPH 446_ PAATA 451_ LHAEL 456_ CQAGS 461_ SQGLS 466_ LCQFQ 471_ NFSLH 476_ DPLYG 481_ KLFST 486_ YLRPP 491_ HTSRG 496_ TSQTP 501_ NASSP 506_ GNPTA 511_ LANGT 516_VQAPK
1: Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors