Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
1_MTTAV 6_ ERKYI 11_ NIRKR 16_ LDQLG 21_ YRQTL 26_ TVECL 31_ PLVEK 36_ LFSDL 41_ VHTTE 46_ SLRQS 51_ KLSAV 56_ KAEKE 61_ SANFD 66_ FVLEP 71_ YKLEN 76_ ARLSR 81_ ENNEL 86_ YLELM 91_ KLREH 96_ SDQHV 101_ KELKT 106_ SLKKC 111_ ARETA 116_ DLKFL 121_ NNQYA 126_ HKLKL 131_ LEKES 136_ KAKNE 141_ RIQQL 146_ QEKNL 151_ HAVVQ 156_ TPGGK 161_ KRSIA 166_ FRRQR 171_ MQIDE 176_ PVPPS 181_ EVSSY 186_ PVPQP 191_ DDPYI 196_ ADLLQ 201_ VADNR 206_ IQELQ 211_ QEVHQ 216_ LQEKL 221_ AMMES 226_ GVRDY 231_ SKQIE 236_ LRERE 241_ IERLS 246_ VALDG 251_ GRSPD 256_ VLSLE 261_ SRNKT 266_ NEKLI 271_ AHLNI 276_ QVDFL 281_ QQANK 286_ DLEKR 291_ IRELM 296_ ETKET 301_ VTSEV 306_ VNLSN 311_ KNEKL 316_ CQELT 321_ EIDQL 326_ AQQLE 331_ RHKEE 336_ VLETA 341_ DKELG 346_ EAKKE 351_ IKRKL 356_ SEMQD 361_ LEETM 366_ AKLQL 371_ ELNLC 376_ QKEKE 381_ RLSDE 386_ LLVKS 391_ DLETV 396_ VHQLE 401_ QEKQR 406_ LSKKV 411_ ESFAV 416_ TERQL 421_ TLEVE 426_ RMRLE 431_ HGIKR 436_ RDRSP 441_ SRLDT 446_ FLKGI 451_ EEERD 456_ YYKKE 461_ LERLQ 466_ HIIQR 471_ RSCST 476_ SYSAR 481_ EKSSI 486_ FRTPE 491_ KGDYN 496_ SEIHQ 501_ ITRER 506_ DELQR 511_ MLERF 516_ EKYME 521_ DIQSN 526_ VKLLT 531_ AERDK 536_ LSVLY 541_ NEAQE 546_ ELSAL 551_ RKEST 556_ QTTAP 561_ HNIVS 566_ LMEKE 571_ KELAL 576_ SDLRR 581_ IMAEK 586_ EALRE 591_ KLEHI 596_ EEVSL 601_ FGKSE 606_ LEKTI 611_ EHLTC 616_ VNHQL 621_ ESEKY 626_ ELKSK 631_ VLIMK 636_ ETIES 641_ LENKL 646_ KVQAQ 651_ KFSHV 656_ AGDSS 661_ HQKTE 666_ VNSLR 671_ IVNEQ 676_ LQRSV 681_ DDYQH 686_ RLSIK 691_ RGELE 696_ SAQAQ 701_ IKILE 706_ EKIDE 711_ LNLKM 716_ TSQDE 721_ EAHVM 726_ KKTIG 731_ VIDKE 736_ KDFLQ 741_ ETVDE 746_ KTEKI 751_ ANLQE 756_ NLANK 761_ EKAVA 766_ QMKIM 771_ ISECE 776_ SSVNQ 781_ LKETL 786_ VNRDR 791_ EINSL 796_ RRQLD 801_ AAHKE 806_ LDEVG 811_ RSREI 816_ AFKEN 821_ RRLQD 826_ DLATM 831_ ARENQ 836_ EISLE 841_ LEAAV 846_ QEKEE 851_ MKSRV 856_ HKYIT 861_ EVSRW 866_ ESLMA 871_ AKEKE 876_ NQDLL 881_ DRFQM 886_ LHNRA 891_ EDWEV 896_ KAHQA 901_ EGESS 906_ SVRLE 911_ LLSID 916_ TERRH 921_ LRERV 926_ ELLEK 931_ EIQEH 936_ INAHH 941_ AYESQ 946_ ISSMA 951_ KAMSR 956_ LEEEL 961_ RHQED 966_ EKATV 971_ LNDLS 976_ SLREL 981_ CIKLD 986_ SGKDI 991_ MTQQL 996_ NSKNL 1001_ EFERV 1006_ VVELE 1011_ NVKSE 1016_ SDLLK 1021_ KQLSN 1026_ ERHTV 1031_ KNLES 1036_ LLATN 1041_ RDKEF 1046_ HSHLT 1051_ SHEKD 1056_ TEIQL 1061_ LKEKL 1066_ TLSES 1071_ KLTSQ 1076_ SRENT 1081_ MLRAK 1086_ VAQLQ 1091_ TDYDA 1096_ LKRQI 1101_ STERY 1106_ ERERA 1111_ IQEMR 1116_ RHGLA 1121_ TPPLS 1126_ STLRS 1131_PSHSP
1: Centrosomal microtubule-binding protein involved in centriole biogenesis (PubMed:27477386). Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner (PubMed:27185865)