Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]
1_MNTDL 6_ AAGKM 11_ ASAAC 16_ SMDPI 21_ DSFEL 26_ LDLLF 31_ DRQDG 36_ ILRHV 41_ ELGEG 46_ WGHVK 51_ DQQVL 56_ PNPDS 61_ DDFLS 66_ SILGS 71_ GDSLP 76_ SSPLW 81_ SPEGS 86_ DSGIS 91_ EDLPS 96_ DPQDT 101_ PPRSG 106_ PATSP 111_ AGCHP 116_ AQPGK 121_ GPCLS 126_ YHPGN 131_ SCSTT 136_ TPGPV 141_ IQVPE 146_ ASVTI 151_ DLEMW 156_ SPGGR 161_ ICAEK 166_ PADPV 171_ DLSPR 176_ CNLTV 181_ KDLLL 186_ SGSSG 191_ DLQQH 196_ HLGAS 201_ YLLRP 206_ GAGHC 211_ QELVL 216_ TEDEK 221_ KLLAK 226_ EGITL 231_ PTQLP 236_ LTKYE 241_ ERVLK 246_ KIRRK 251_ IRNKQ 256_ SAQES 261_ RKKKK 266_ EYIDG 271_ LETRM 276_ SACTA 281_ QNQEL 286_ QRKVL 291_ HLEKQ 296_ NLSLL 301_ EQLKK 306_ LQAIV 311_ VQSTS 316_ KSAQT 321_ GTCVA 326_ VLLLS 331_ FALII 336_ LPSIS 341_ PFGPN 346_ KTESP 351_ GDFAP 356_ VRVFS 361_ RTLHN 366_ DAASR 371_ VAADA 376_ VPGSE 381_ APGPR 386_ PEADT 391_ TREES 396_ PGSPG 401_ ADWGF 406_ QDTAN 411_ LTNST 416_ EELDN 421_ ATLVL 426_ RNATE 431_ GLGQV 436_ ALLDW 441_ VAPGP 446_ STGSG 451_ RAGLE 456_AAGDE
1: Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). May function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. Regulates FGF21 transcription (By similarity). Plays a crucial role in the regulation of triglyceride metabolism and is required for the maintenance of normal plasma triglyceride concentrations (PubMed:21666694)