Gene name: REP15

Uniprot entry:

Q6BDI9

Protein names:

Rab15 effector protein

Protein sequence:

1_MGQKA 6_ SQQLA 11_ LKDSK 16_ EVPVV 21_ CEVVS 26_ EAIVH 31_ AAQKL 36_ KEYLG 41_ FEYPP 46_ SKLCP 51_ AANTL 56_ NEIFL 61_ IHFIT 66_ FCQEK 71_ GVDEW 76_ LTTTK 81_ MTKHQ 86_ AFLFG 91_ ADWIW 96_ TFWGS 101_ NKQIK 106_ LQLAV 111_ QTLQM 116_ SSPPP 121_ VESKP 126_ CDLSN 131_ PESRV 136_ EESSW 141_ KKSRF 146_ DKLEE 151_ FCNLI 156_ GEDCL 161_ GLFII 166_ FGMPG 171_ KPKDI 176_ RGVVL 181_ DSVKS 186_ QMVRS 191_ HLPGG 196_ KAVAQ 201_ FVLET 206_ EDCVF 211_ IKELL 216_ RNCLS 221_ KKDGL 226_ REVGK 231_VYISI

Protein annotations

Protein functions:

1: Effector that interacts with Rab GTPases in their active form (GTP-bound) including RAB15, RAB3A-D and RAB34. Controls downstream signaling such as cell proliferation and cell migration (PubMed:35871249). Also regulates transferrin receptor recycling from the endocytic recycling compartment (PubMed:16195351, PubMed:35871249)