Transmembrane protein PVRIG (CD112 receptor) (CD112R) (Poliovirus receptor-related immunoglobulin domain-containing protein)
1_MRTEA 6_ QVPAL 11_ QPPEP 16_ GLEGA 21_ MGHRT 26_ LVLPW 31_ VLLTL 36_ CVTAG 41_ TPEVW 46_ VQVRM 51_ EATEL 56_ SSFTI 61_ RCGFL 66_ GSGSI 71_ SLVTV 76_ SWGGP 81_ NGAGG 86_ TTLAV 91_ LHPER 96_ GIRQW 101_ APARQ 106_ ARWET 111_ QSSIS 116_ LILEG 121_ SGASS 126_ PCANT 131_ TFCCK 136_ FASFP 141_ EGSWE 146_ ACGSL 151_ PPSSD 156_ PGLSA 161_ PPTPA 166_ PILRA 171_ DLAGI 176_ LGVSG 181_ VLLFG 186_ CVYLL 191_ HLLRR 196_ HKHRP 201_ APRLQ 206_ PSRTS 211_ PQAPR 216_ ARAWA 221_ PSQAS 226_ QAALH 231_ VPYAT 236_ INTSC 241_ RPATL 246_ DTAHP 251_ HGGPS 256_ WWASL 261_ PTHAA 266_ HRPQG 271_ PAAWA 276_ STPIP 281_ ARGSF 286_ VSVEN 291_ GLYAQ 296_ AGERP 301_ PHTGP 306_ GLTLF 311_ PDPRG 316_ PRAME 321_GPLGV
1: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding