AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3)
1_MAQET 6_ NHSQV 11_ PMLCS 16_ TGCGF 21_ YGNPR 26_ TNGMC 31_ SVCYK 36_ EHLQR 41_ QNSSN 46_ GRISP 51_ PATSV 56_ SSLSE 61_ SLPVQ 66_ CTDGS 71_ VPEAQ 76_ SALDS 81_ TSSSM 86_ QPSPV 91_ SNQSL 96_ LSESV 101_ ASSQL 106_ DSTSV 111_ DKAVP 116_ ETEDV 121_ QASVS 126_ DTAQQ 131_ PSEEQ 136_ SKSLE 141_ KPKQK 146_ KNRCF 151_ MCRKK 156_ VGLTG 161_ FECRC 166_ GNVYC 171_ GVHRY 176_ SDVHN 181_ CSYNY 186_ KADAA 191_ EKIRK 196_ ENPVV 201_VGEKI
1: Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity)