Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein)
1_MAHQT 6_ GIHAT 11_ EELKE 16_ FFAKA 21_ RAGSV 26_ RLIKV 31_ VIEDE 36_ QLVLG 41_ ASQEP 46_ VGRWD 51_ QDYDR 56_ AVLPL 61_ LDAQQ 66_ PCYLL 71_ YRLDS 76_ QNAQG 81_ FEWLF 86_ LAWSP 91_ DNSPV 96_ RLKML 101_ YAATR 106_ ATVKK 111_ EFGGG 116_ HIKDE 121_ LFGTV 126_ KDDLS 131_ FAGYQ 136_ KHLSS 141_ CAAPA 146_ PLTSA 151_ ERELQ 156_ QIRIN 161_ EVKTE 166_ ISVES 171_ KHQTL 176_ QGLAF 181_ PLQPE 186_ AQRAL 191_ QQLKQ 196_ KMVNY 201_ IQMKL 206_ DLERE 211_ TIELV 216_ HTEPT 221_ DVAQL 226_ PSRVP 231_ RDAAR 236_ YHFFL 241_ YKHTH 246_ EGDPL 251_ ESVVF 256_ IYSMP 261_ GYKCS 266_ IKERM 271_ LYSSC 276_ KSRLL 281_ DSVEQ 286_ DFHLE 291_ IAKKI 296_ EIGDG 301_ AELTA 306_ EFLYD 311_ EVHPK 316_ QHAFK 321_ QAFAK 326_ PKGPG 331_ GKRGH 336_ KRLIR 341_GPGEN
1: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity)