Sulfotransferase 1C3 (ST1C3) (EC 2.8.2.1) (EC 2.8.2.2)
1_MAKIE 6_ KNAPT 11_ MEKKP 16_ ELFNI 21_ MEVDG 26_ VPTLI 31_ LSKEW 36_ WEKVC 41_ NFQAK 46_ PDDLI 51_ LATYP 56_ KSGTT 61_ WMHEI 66_ LDMIL 71_ NDGDV 76_ EKCKR 81_ AQTLD 86_ RHAFL 91_ ELKFP 96_ HKEKP 101_ DLEFV 106_ LEMSS 111_ PQLIK 116_ THLPS 121_ HLIPP 126_ SIWKE 131_ NCKIV 136_ YVARN 141_ PKDCL 146_ VSYYH 151_ FHRMA 156_ SFMPD 161_ PQNLE 166_ EFYEK 171_ FMSGK 176_ VVGGS 181_ WFDHV 186_ KGWWA 191_ AKDMH 196_ RILYL 201_ FYEDI 206_ KKDPK 211_ REIEK 216_ ILKFL 221_ EKDIS 226_ EEILN 231_ KIIYH 236_ TSFDV 241_ MKQNP 246_ MTNYT 251_ TLPTS 256_ IMDHS 261_ ISPFM 266_ RKGMP 271_ GDWKN 276_ YFTVA 281_ QNEEF 286_ DKDYQ 291_ KKMAG 296_STLTF
1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor. Has sulfotransferase activity towards various substrates, such as bile acids, thyroid hormones and toward xenobiotic compounds such as chloro phenols and hydroxypyrenes. Lithocholic acid appears to be the best substrate among the endogenous compounds tested and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol shows the highest specific activity among the xenobiotic compounds
2: Exhibits weak sulphating activity and only toward chloro phenols (pentachlorophenol and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol)