Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4)
1_MGCCG 6_ CSGGC 11_ GSGCG 16_ GCGSG 21_ CGGCG 26_ SGCGG 31_ CGSGC 36_ GGCGS 41_ GCGGC 46_ GSSCC 51_ VPICC 56_ CKPVC 61_ CCVPA 66_ CSCSS 71_ CGSCG 76_ GSKGG 81_ YGSCG 86_ GSKGG 91_ CVSCG 96_ GSKGG 101_ CGSCG 106_ GSKGG 111_ CGSCG 116_ GSKGG 121_ CGSCG 126_ GSKGG 131_ CVSCG 136_ GSKGG 141_ CGSCG 146_ GSKGG 151_ CVSCG 156_ GSKGG 161_ CGSCG 166_ GSKGG 171_ CGSCG 176_ GSKGG 181_ CGSCG 186_ GSKGG 191_ CGSCG 196_ CSQCS 201_ CCKPC 206_ CCSSG 211_ CGSSC 216_ CQSSC 221_ CKPCC 226_ SSSGC 231_ GSSCC 236_ QSSCC 241_ KPYCC 246_ QSSCC 251_ KPCCS 256_ SSGCG 261_ SSCCQ 266_ SSCCN 271_ PCCSQ 276_ SSCCV 281_PVCCQ
1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins