Gene name: KRTAP5-1

Uniprot entry:

Q6L8H4

Protein names:

Keratin-associated protein 5-1 (Keratin, cuticle, ultrahigh sulphur 1-like) (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1)

Protein sequence:

1_MGCCG 6_ CSGGC 11_ GSSCG 16_ GCGSG 21_ CGGCG 26_ SGCGG 31_ CGSGC 36_ GGSGS 41_ SCCVP 46_ VCCCK 51_ PVCCR 56_ VPTCS 61_ CSSCG 66_ KGGCG 71_ SSGGS 76_ KGGCG 81_ SCGGC 86_ KGGCG 91_ SCGGS 96_ KGGCG 101_ SCGGS 106_ KGGCG 111_ SCGGS 116_ KGGCG 121_ SGCGG 126_ CGSSC 131_ CVPVC 136_ CCKPM 141_ CCCVP 146_ ACSCS 151_ SCGKG 156_ GCGSC 161_ GCSKG 166_ ACGSC 171_ GGSKG 176_ GCGSC 181_ GGCKG 186_ GCGSC 191_ GGSKG 196_ GCGSG 201_ CGGCG 206_ SGCGV 211_ PVCCC 216_ SCSSC 221_ GSCAG 226_ SKGGC 231_ GSSCS 236_ QCSCC 241_ KPCCC 246_ SSGCG 251_ SSCCQ 256_ SSCCK 261_ PCCSQ 266_ SSCCV 271_PVCCQ

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins