MRN complex-interacting protein (MRN-interacting protein)
1_MASLQ 6_ RSRVL 11_ RCCSC 16_ RLFQA 21_ HQVKK 26_ SVKWT 31_ CKACG 36_ EKQSF 41_ LQAYG 46_ EGSGA 51_ DCRRH 56_ VQKLN 61_ LLQGQ 66_ VSELP 71_ LRSLE 76_ ETVSA 81_ SEEEN 86_ VGHQQ 91_ AGNVK 96_ QQEKS 101_ QPSES 106_ RWLKY 111_ LEKDS 116_ QELEL 121_ EGTGV 126_ CFSKQ 131_ PSSKM 136_ EEPGP 141_ RFSQD 146_ LPRKR 151_ KWSRS 156_ TVQPP 161_ CSRGV 166_ QDSGG 171_ SEVAW 176_ GPQKG 181_ QAGLT 186_ WKVKQ 191_ GSSPC 196_ LQENS 201_ ADCSA 206_ GELRG 211_ PGKEL 216_ WSPIQ 221_ QVTAT 226_ SSKWA 231_ QFVLP 236_ PRKSS 241_ HVDSE 246_ QPRSL 251_ QRDPR 256_ PAGPA 261_ QAKQG 266_ TPRAQ 271_ ASREG 276_ LSRPT 281_ AAVQL 286_ PRATH 291_ PVTSG 296_ SERPC 301_ GKTSW 306_ DARTP 311_ WAEGG 316_ PLVLE 321_ AQNPR 326_ PTRLC 331_ DLFIT 336_GEDFD
1: Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex (PubMed:27568553). Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair (PubMed:27568553)