Fanconi anemia core complex-associated protein 20 (FANCA-associated protein of 20 kDa) (Fanconi anemia-associated protein of 20 kDa)
1_MEAAR 6_ RPRLG 11_ LSRRR 16_ PRPAG 21_ GPSGG 26_ RPWFL 31_ LGGDE 36_ RERLW 41_ AELLR 46_ TVSPE 51_ LILDH 56_ EVPSL 61_ PAFPG 66_ QEPRC 71_ GPEPT 76_ EVFTV 81_ GPKTF 86_ SWTPF 91_ PPDLW 96_ GPGRS 101_ YRLLH 106_ GAGGH 111_ LESPA 116_ RSLPQ 121_ RPAPD 126_ PCRAP 131_ RVEQQ 136_ PSVEG 141_ AAALR 146_ SCPMC 151_ QKEFA 156_ PRLTQ 161_ LDVDS 166_ HLAQC 171_LAEST
1: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1