Gene name: FBXL22

Uniprot entry:

Q6P050

Protein names:

F-box and leucine-rich protein 22

Protein sequence:

1_MWPLL 6_ TMHIT 11_ QLNRE 16_ CLLHL 21_ FSFLD 26_ KDSRK 31_ SLART 36_ CSQLH 41_ DVFED 46_ PALWS 51_ LLHFR 56_ SLTEL 61_ QKDNF 66_ LLGPA 71_ LRSLS 76_ ICWHS 81_ SRVQV 86_ CSIED 91_ WLKSA 96_ FQRSI 101_ CSRHE 106_ SLVND 111_ FLLRV 116_ CDRLS 121_ AVRSP 126_ RRREA 131_ PAPSS 136_ GTPIA 141_ VGPKS 146_ PRWGG 151_ PDHSE 156_ FADLR 161_ SGVTG 166_ ARAAA 171_ RRGLG 176_ SLRAE 181_ RPSET 186_ PPAPG 191_ VSWGP 196_ PPPGA 201_ PVVIS 206_ VKQEE 211_ GKQGR 216_ TGRRS 221_ HRAAP 226_ PCGFA 231_ RTRVC 236_ PPTFP 241_GADAF

Protein annotations

Protein functions:

1: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC)