Heme transporter HRG1 (Heme-responsive gene 1 protein homolog) (HRG-1) (hHRG-1) (Solute carrier family 48 member 1)
1_MAPSR 6_ LQLGL 11_ RAAYS 16_ GISSV 21_ AGFSI 26_ FLVWT 31_ VVYRQ 36_ PGTAA 41_ MGGLA 46_ GVLAL 51_ WVLVT 56_ HVMYM 61_ QDYWR 66_ TWLKG 71_ LRGFF 76_ FVGVL 81_ FSAVS 86_ IAAFC 91_ TFLVL 96_ AITRH 101_ QSLTD 106_ PTSYY 111_ LSSVW 116_ SFISF 121_ KWAFL 126_ LSLYA 131_ HRYRA 136_ DFADI 141_SILSD
1: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment (PubMed:18418376). In macrophages of the reticuloendothelial system, is the heme transporter for heme-iron recycling. Essential for macrophage iron homeostasis, transports heme from the phagolysosome to the cytoplasm during erythrophagocytosis (EP) (PubMed:23395172)